Browse the latest research summaries in the field of veterinary medicine for spinal cord injury patients and caregivers.
Showing 81-90 of 90 results
Vet. Sci., 2024 • April 26, 2024
Musculoskeletal injuries in sport horses pose significant challenges, often leading to performance losses and affecting the horse's overall well-being, with social and economic implications. A compreh...
KEY FINDING: Musculoskeletal injuries are prevalent in sport horses, impacting their ability to return to exercise. Equine medicine has rapidly developed diverse therapeutic options for these problems.
BMC Veterinary Research, 2015 • March 7, 2015
This study evaluated the feasibility and safety of intrathecal transplantation of autologous bone marrow mesenchymal stem cells (BM-MSCs) in horses. The results of the study showed no clinical or neur...
KEY FINDING: Intrathecal transplantation of autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) in horses is feasible and safe.
Neural Regeneration Research, 2015 • February 1, 2015
This study explores the effects of electroacupuncture on spinal cord neuronal injury in a rat model of intervertebral disc extrusion, emphasizing the importance of microcirculation. The results indica...
KEY FINDING: Electroacupuncture significantly increased blood flow in the L1 segment of the spinal cord in rats with intervertebral disc extrusion.
J Vet Sci, 2017 • September 1, 2017
The study demonstrates that transplantation of canine MSCs overexpressing HO-1 promotes functional recovery after SCI in dogs. The improved recovery is associated with enhanced anti-inflammatory activ...
KEY FINDING: Dogs receiving MSCs overexpressing HO-1 (MSC-HO-1) showed significantly improved functional recovery at 7 weeks after transplantation compared to the control group.
PNAS, 2017 • October 24, 2017
This study investigates the persistence and functionality of thin myelin sheaths, a hallmark of remyelination, in two animal models. The research addresses the question of whether these thin sheaths c...
KEY FINDING: Thin myelin sheaths persist for up to 13 years in dogs with a genetic myelin disorder without causing axon degeneration.
Scientific Reports, 2017 • November 1, 2017
This study aimed to evaluate the feasibility and reliability of standardized motor evoked potential (MEP) recording and analysis in neonatal lambs. The researchers developed an algorithm for MEP quant...
KEY FINDING: MEPs could be easily recorded in neonatal lambs using transcranial motor cortex stimulation.
PLoS ONE, 2019 • March 6, 2019
This study compares three methods for harvesting olfactory ensheathing cells (OECs) from the olfactory mucosa in dogs: rhinotomy, keyhole approach, and rhinoscopy. All three methods appear safe and pr...
KEY FINDING: The keyhole approach and rhinoscopy yielded similar proportions and populations of p75-positive cells, presumed to be olfactory ensheathing cells.
Cell Transplantation, 2020 • January 1, 2020
This case report describes stem cell-based therapy using autologous adipose tissue-derived mesenchymal stem cells (ADSCs) for chronic spinal cord injury (SCI) treatment in a domestic ferret patient. T...
KEY FINDING: Direct administration of autologous ADSCs into the damaged spinal cord area led to significant neurological and motor improvements in a ferret patient with chronic SCI.
J Vet Res, 2020 • January 1, 2020
This study determined the presence of nitric oxide synthesis isoforms (nNOS, iNOS, and eNOS) in thoracic spinal cord segments and nodose ganglia of rats with gamma-irradiated livers. The nNOS, iNOS, a...
KEY FINDING: nNOS immunoreactivity was found in the superficial lamina (lamina I–II) of the spinal cord of the rats with ionising radiation insult to the liver, and to a lesser extent in lamina III–IV.
CELLULAR REPROGRAMMING, 2010 • December 1, 2010
The study introduces a novel animal model for SCI research using cloned Yucatan minipigs, focusing on sacrocaudal spinal cord transection to induce tail paralysis while preserving other motor function...
KEY FINDING: Transection of the sacrocaudal spinal cord in Yucatan minipigs induces quantifiable tail paralysis without causing impairment in pelvic limb, urinary, or bowel functions.