Browse the latest research summaries in the field of veterinary medicine for spinal cord injury patients and caregivers.
Showing 11-20 of 90 results
Genes, 2022 • September 16, 2022
This study investigates the molecular basis of adipose-derived stem cell (ASC) differentiation into chondrocytes, using canine material, to serve as a transcriptomic reference for further research aim...
KEY FINDING: Several genes (e.g., MMP12, MPEG1, CHI3L1, and CD36) were identified as potential new markers of chondrogenesis. These genes could indicate how culture conditions affect ASCs.
J Vet Intern Med, 2022 • September 1, 2022
The study validates a 50-step walking test as a pragmatic outcome measure for assessing ambulatory recovery in dogs after decompressive surgery for thoracolumbar disc herniation. The test effectively ...
KEY FINDING: The 50-step test effectively distinguished between outcomes for dogs with and without deep pain sensation, predicting recovery and expected recovery times.
Inflammation and Regeneration, 2022 • September 1, 2022
This study explored the therapeutic potential of platelet-rich plasma (PRP) for treating multiple sclerosis (MS) in cats, utilizing an ethidium bromide (EB)-induced demyelination model. The research a...
KEY FINDING: PRP had a significant positive effect on motor function of the hindlimbs, with improvements observed as early as day 20.
PLOS ONE, 2022 • October 18, 2022
This study evaluated the efficacy of topical oclacitinib, in conjunction with nail trimming, for treating murine ulcerative dermatitis (UD) compared to nail trimming alone or nail trimming combined wi...
KEY FINDING: Mean UD scores decreased from day 1 to day 7 and from day 1 to day 14 for all treatment groups, indicating improvement in skin lesions regardless of the treatment.
J. Vet. Med. Sci., 2023 • January 1, 2023
This report describes two cases of spinal cord injury in puppies resulting from inappropriate microchip implantation following the implementation of a revised Animal Welfare and Management Law in Japa...
KEY FINDING: Two puppies experienced spinal cord injuries due to inappropriate microchip implantation following a new law mandating microchipping in Japan.
Animals, 2022 • November 22, 2022
This review provides a comparative overview of neurogenic bladder (NB) in dogs, cats, and humans, focusing on neurological diseases affecting the lower urinary tract. The review covers congenital dise...
KEY FINDING: Spina bifida is associated with urinary incontinence in children, with renal damage and UTIs being the main causes of death. Management focuses on preserving renal function and promoting urinary continence.
J Vet Intern Med, 2023 • March 1, 2023
This study evaluated the efficacy of prophylactic omeprazole in preventing gastrointestinal (GI) complications in dogs undergoing surgery for acute thoracolumbar intervertebral disc extrusion (TL-IVDE...
KEY FINDING: The frequency of GI signs was not significantly different between the omeprazole and placebo groups (P = .59).
Animals, 2023 • April 19, 2023
The main objective of our study was to demonstrate that physiotherapy and assisted gait in supportive devices to maintain the standing position may help paraplegic dogs to develop spinal walking. Afte...
KEY FINDING: After 125 to 320 physiotherapy sessions (25 to 64 weeks), 35 dogs (58.33%) developed SW and were able to walk without falling or falling sometimes in the case of a quick look
J Vet Intern Med, 2023 • July 1, 2023
This study investigates the characteristics of combined disc- and osseous-associated cervical spondylomyelopathy (CSM) in dogs using MRI and neurological examination. The findings indicate that a sign...
KEY FINDING: A substantial percentage of dogs with CSM (26% in this study) present with both IVD protrusion and osseous changes, often at the same location.
BMC Veterinary Research, 2023 • July 12, 2023
The study investigated the long-term changes in Th17 and Treg cells in dogs with spinal cord injury (SCI) after intervertebral disc herniation (IVDH). The findings indicate that while Th17 and Treg ce...
KEY FINDING: Significantly higher levels of Th17 and Treg cells were detected after recovery from IVDH compared to the acute stage.