Browse the latest research summaries in the field of urology for spinal cord injury patients and caregivers.
Showing 31-40 of 407 results
Toxins, 2023 • January 17, 2023
The study found that urethral BoNT-A injections can be effective for treating non-SCI voiding dysfunction, especially in patients with dysfunctional voiding (DV). Patients with detrusor underactivity ...
KEY FINDING: DV patients had a higher success rate (76.6%) than DU (50%) and PRES (45.8%) patients (p = 0.002) after urethral BoNT-A injection.
Toxins, 2023 • January 26, 2023
This study investigates the effectiveness of botulinum toxin A (Botox) injections into either the detrusor muscle or urethral sphincter for treating autonomic dysreflexia (AD) in spinal cord injury (S...
KEY FINDING: Both detrusor and urethral sphincter injections of Botox improved autonomic dysreflexia (AD) in spinal cord injury (SCI) patients, with detrusor injections showing greater improvement.
J. Clin. Med, 2023 • February 10, 2023
This study presents a comprehensive literature review of urologic surgery for neurogenic lower urinary tract dysfunction (NLUTD) in patients with chronic spinal cord injury (SCI). Surgical procedures ...
KEY FINDING: The review highlights various surgical procedures like augmentation cystoplasty, bladder auto-augmentation, and sacral neuromodulation for reducing bladder pressures.
Die Urologie, 2023 • March 3, 2023
The article addresses inconsistencies in the assessment of earning capacity reduction (MdE) for neurourological injuries within the German and Austrian statutory accident insurance systems. A working ...
KEY FINDING: The study produced diagnostic foundations for legally sound assessment of accident consequences in neurourology.
PLoS ONE, 2023 • March 9, 2023
The study aimed to identify BPH patients who require adrenergic alpha-blockers and antispasmodics for at least three months after receiving surgery using preoperative and perioperative data. The resul...
KEY FINDING: Chronic kidney disease (CKD) is associated with increased postoperative usage of adrenergic alpha-blockers.
J. Clin. Med., 2023 • March 3, 2023
This review provides an overview of non-surgical management options for neurogenic lower urinary tract dysfunction (NLUTD) in chronic spinal cord injury (SCI) patients. It emphasizes minimally invasiv...
KEY FINDING: Conservative management of NLUTD includes physical therapy (pelvic floor muscle training), antimuscarinic drugs, desmopressin, β3-Adrenoceptor Agonists and neuromodulation.
CNS Neurosci Ther, 2024 • July 17, 2024
The study aimed to examine the involvement of L- and T-type VGCCs in the improvement of DSD following administration of 2,5-dimethoxy-4-iodophenyl-2-aminopropane hydrochloride in SCI rats. Intrathecal...
KEY FINDING: Intrathecal administration of 2,5-dimethoxy-4-iodophenyl-2-aminopropane hydrochloride or nifedipine increased voiding volume and enhanced voiding efficiency in rats with SCI.
Toxins, 2023 • April 17, 2023
This review summarizes the application of botulinum toxin A (BoNT-A) injections for managing lower urinary tract symptoms (LUTS) in spinal cord injury (SCI) patients, addressing both therapeutic effic...
KEY FINDING: Detrusor BoNT-A injection can decrease daily incontinence episodes, the frequency of clean intermittent catheterization (CIC), and maximal detrusor pressure while increasing cystometric bladder capacity and reflux volume.
bioRxiv, 2023 • November 17, 2023
This study investigates the potential of ampakines to improve bladder function following spinal cord injury (SCI) in rats. The research focuses on the acute effects of intravenous ampakine administrat...
KEY FINDING: Ampakine CX1739 significantly reduced the pressure threshold for inducing bladder contraction in rats with SCI.
Biomedicines, 2023 • June 5, 2023
This study demonstrates that OAB patients have deficits in resting-state brain connectivity compared to healthy controls. Large-scale brain networks, such as the DMN and the SAN, and their interaction...
KEY FINDING: OAB patients had a weaker presence of the salience network (SAN) and default mode network (DMN).