Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.
Showing 601-610 of 614 results
Neural Regen Res, 2019 • April 1, 2019
This study aimed to establish and verify a surgical prognostic model for cervical spinal cord injury without radiological abnormality. The model uses factors like cervical stenosis, JOA score, and dis...
KEY FINDING: A prognostic model was established: logit(P) = −25.4545 + 21.2576VALUE + 1.2160SCORE − 3.4224TIME, where VALUE is the Pavlov ratio, SCORE is the JOA score, and TIME is disease duration.
Scientific Reports, 2019 • June 13, 2019
The study aimed to validate a fetal lamb model for spina bifida (SB) research, comparing two surgical models (with and without myelotomy) to normal lambs. The myelotomy model best phenocopied the anat...
KEY FINDING: The myelotomy model best replicates the anatomy, pathophysiology, and symptoms of non-cystic spina bifida (SB).
Innov Surg Sci, 2017 • February 25, 2017
This study demonstrates the effectiveness of Fluoro-Ruby (FR) as a reliable fluorescent marker for studying ascending regenerated fibers in the spinal cord axonal regeneration. FR allows for easy nerv...
KEY FINDING: FR effectively labels ascending fibers in the dorsal columns of the rat spinal cord, including regenerated fibers crossing injury sites.
International Journal of Surgery Case Reports, 2020 • December 12, 2019
This case report presents the successful treatment of a vertebral body defect (VBD) in a 27-year-old female using umbilical cord-derived mesenchymal stem cells (UC-MSCs) combined with hydroxyapatite s...
KEY FINDING: The patient could walk and had no pain three months post-surgery.
Journal of Medicine and Life, 2019 • October 1, 2019
The study aimed to replicate Brunelli's CNS-PNS grafting paradigm in rats, investigating the potential benefits of graft-induced neuroregeneration of denervated skeletal muscle and the effect of Cereb...
KEY FINDING: Brunelli’s concept was successfully replicated, demonstrating the first graft induced existence of cholinergic and glutamatergic neurotransmission in denervated grafted muscles.
Ann Transl Med, 2020 • March 1, 2020
The study established a mouse model of SCI involving a crush injury followed by scar removal to simulate clinical treatment of SCI. The model was validated using BMS scoring, electrophysiology, and hi...
KEY FINDING: The initial crush injury model resulted in significant neurological deficits with limited natural recovery, as evidenced by behavioral scoring and electrophysiology.
Cureus, 2020 • October 27, 2020
ESWT shows promise in increasing bone mineral density in osteoporosis patients and reducing pain associated with heterotopic ossification after spinal cord injury. ESWT can improve range of motion and...
KEY FINDING: ESWT may increase bone mineral density (BMD) in patients with osteoporosis, potentially prolonging the asymptomatic period of vertebral body compressive changes and radicular symptoms.
Prenatal Diagnosis, 2021 • January 1, 2021
This systematic review and meta-analysis evaluated the safety and efficacy of stem cell transplantation in animal models of MMC, finding beneficial effects on animal survival, defect coverage, and spi...
KEY FINDING: Intra-amniotic injection of allogeneic amniotic fluid mesenchymal stem cells (AF-MSCs) in the fetal rat model did not compromise fetal survival.
Eur Spine J, 2003 • November 19, 2002
This case report describes a 48-year-old man with an intramedullary schwannoma extending from the conus medullaris to T11, causing bilateral lower extremity weakness. Gross total resection of the tumo...
KEY FINDING: Schwann cells can indeed invade the central nervous system, as demonstrated by the presence of an intramedullary schwannoma within the conus medullaris.
Spine (Phila Pa 1976), 2008 • November 15, 2008
This study evaluates the stability of implanted scaffolds and the extent of kyphoscoliotic deformities after spinal fixation in a rat model of spinal cord injury. The researchers implanted radio-opaqu...
KEY FINDING: Spinal fixation significantly reduced scoliosis in the fixed group (1.89 ± 0.75°) compared to the unfixed group (8.13 ± 2.03°).