Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.
Showing 591-600 of 614 results
Acta Neurochirurgica, 2018 • January 12, 2018
This study introduces a new, minimal invasive, CT-guided spinal cord injury procedure for minipigs, using a balloon catheter to compress the spinal cord. The procedure was standardized and resulted in...
KEY FINDING: The CT-guided balloon compression technique successfully induced complete spinal cord injuries in minipigs.
Therapeutics and Clinical Risk Management, 2018 • January 1, 2018
This prospective safety study evaluated the impact of BMP-7 on cytokine expression in non-union therapy by comparing IGF-1, PDGF-AB, and TGF-β levels in patients treated with ABG alone versus ABG with...
KEY FINDING: IGF-1 levels were generally higher in the ABG-only group (G2) compared to the BMP-7 group (G1), but the overall course of expression was similar.
中国修复重建外科杂志, 2017 • March 1, 2017
This study aimed to explore the impact of short-term low-frequency electrical stimulation (SLES) on the regenerative capabilities of chronic peripheral nerve defects. The study found that SLES can pro...
KEY FINDING: SLES upregulates GAP-43 and BDNF expression in motor and sensory neurons faster than the control group in the early stages after nerve repair.
Trials, 2018 • May 10, 2018
This study is a randomized controlled trial designed to evaluate the non-inferiority of bioactive glass (BaG) compared to autologous bone graft (ABG) in treating tibial and femoral non-unions using th...
KEY FINDING: The primary endpoint of the study is union achieved 1 year after surgery.
J Spine Surg, 2018 • June 1, 2018
This case report describes a rare complication of total lumbar disc replacement (TDR), where the viscoelastic nucleus of the artificial disc herniated, causing nerve compression and radiculopathy. The...
KEY FINDING: The case report presents an unreported complication of lumbar TDR involving herniation of the viscoelastic nucleus, mimicking a disc herniation.
Diagnostics, 2018 • August 24, 2018
This study investigates the potential of contrast-enhanced ultrasound (CEUS) and cytokine expression analysis (CEA) to predict the outcome of non-union therapy in tibial non-unions. The results sugges...
KEY FINDING: Lower TNF-α expression before surgery was associated with a positive response to non-union therapy.
Asian Journal of Neurosurgery, 2018 • October 1, 2018
This study investigates the effects of spinal cord-derived neural precursor cells (NPCs) transplantation on SCI in after and before injury injection. Our results indicate that NPCs infusion both pre‑ ...
KEY FINDING: NPCs infusion both before and after SCI could decrease the level of inflammatory cytokines, indicating a modulatory effect on inflammation.
Adv Mater, 2019 • January 1, 2019
Advances in biomaterial synthesis, stem cell biology, bioimaging, microsurgery, and microscale technologies have made minimally invasive therapeutics a viable tool in regenerative medicine. Therapeuti...
KEY FINDING: Needles have been utilized to deliver cell-laden biomaterials into the body.
Neural Regen Res, 2019 • April 1, 2019
This study investigated the effectiveness of different nerve transposition techniques in repairing long-segment ulnar nerve defects in rats. The musculocutaneous nerve, medial pectoral nerve, muscular...
KEY FINDING: Repairing a long ulnar nerve defect with different donor nerve transpositions can restore axonal function.
Neural Regen Res, 2019 • April 1, 2019
The study aimed to observe the effect of nerve regeneration and motor function recovery after several types of nerve transposition for median nerve defect. Results showed that wrist flexion function w...
KEY FINDING: Wrist flexion function was restored in all three nerve transposition groups and the epineurial neurorrhaphy group.