Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.
Showing 581-590 of 614 results
Materials Today Bio, 2025 • February 3, 2025
This review discusses the use of hydrogels in spinal surgery for treating intervertebral disc degeneration, spinal cord injury, and dural injury, highlighting their potential for mechanical support an...
KEY FINDING: Hydrogels can provide mechanical support to the spine, fill defects, and facilitate localized drug delivery, enhancing therapeutic effects while reducing adverse reactions.
European Journal of Trauma and Emergency Surgery, 2025 • January 11, 2025
This study investigates the use of periosteal flaps (PF) to enhance bone healing in non-unions, comparing a vascularized (pedicled) PF to a ligated PF and a control group in a rat femur model. The res...
KEY FINDING: The pedicled periosteal flap (PF) group showed a significantly higher bone volume compared to the other groups after 10 weeks.
Journal of Craniovertebral Junction and Spine, 2024 • January 15, 2025
The study compared radiographic outcomes and subsidence rates between hyperlordotic and standard lordotic interbody spacers in ACDF patients. Hyperlordotic spacers led to increased cervical lordosis a...
KEY FINDING: Hyperlordotic spacers resulted in a significantly higher cervical lordosis (CL) at 1-year post-surgery compared to standard lordotic spacers.
World J Stem Cells, 2015 • January 26, 2015
Stem cells are an increasingly feasible option for treating spinal disorders, with potential in regenerating degenerated disks, healing spinal cord injuries, and aiding bone growth in spinal fusion. S...
KEY FINDING: Mesenchymal stem cells (MSCs) can differentiate into osteoblasts and have a significant effect on spinal fusion.
Neural Plasticity, 2016 • May 17, 2016
The study evaluates the effectiveness of fibrin sealant in repairing neonatal sciatic nerve injuries in rats, comparing commercial and snake venom-derived sealants. Results indicate that fibrin sealan...
KEY FINDING: Fibrin sealant coaptation preserves synaptic covering on lesioned motoneurons and promotes neuronal survival.
Neural Regeneration Research, 2016 • August 1, 2016
This study used high-resolution aCGH to identify pathogenic CNVs in samples from patients with typical TCS. Our findings suggest an association between certain CNVs and nervous system disease. Ours st...
KEY FINDING: Array-based comparative genomic hybridization can be used to diagnose tethered spinal cord syndrome.
BioMed Research International, 2016 • October 17, 2016
This study investigated the spatiotemporal changes of CGRP during spinal fusion to explore its role in bone regeneration. The results demonstrated that the early stage of normal spinal fusion is accom...
KEY FINDING: The density of CGRP reached its peak on the 21st day after the spinal fusion surgery in rats.
Spinal Cord Series and Cases, 2015 • October 8, 2015
This study highlights the increasing prevalence of Charcot spinal arthropathy (CSA) in patients with spinal cord injuries (SCI). It emphasizes the importance of understanding initial symptoms, risk fa...
KEY FINDING: Charcot spinal arthropathy (CSA) is most likely increasing in patients suffering from consequences of spinal cord injury.
Neural Regeneration Research, 2016 • December 1, 2016
Early surgical management seems to be justified in most SCI patients. In recent years, the current practice changed towards “ultra-early decompression” and we have seen a paradigm shift, where clinica...
KEY FINDING: Early decompression (within 24 hours) positively influences neurological outcome compared to later intervention without increasing complication rates.
Physiol Rep, 2017 • May 1, 2017
This study investigated how musculotendon adaptations and spinal reflex reorganization influence outcomes after agonist-to-antagonist tendon transfer in cats. The main findings revealed the formation ...
KEY FINDING: New tendinous connections formed after tendon transfer, often near original insertion sites, potentially compromising the mechanical action of the transferred muscle.