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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Surgery Research

Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.

Showing 571-580 of 614 results

SurgeryOrthopedicsMusculoskeletal Medicine

Effect of mechanical stimulation on tissue heterotopic ossification: an in vivo experimental study

Frontiers in Physiology, 2023 • October 11, 2023

This study investigates the role of mechanical stimulation in heterotopic ossification (HOTL) using a mouse model with Enpp1 gene deficiency. The mice were subjected to spinal immobilization and tread...

KEY FINDING: Spinal immobilization effectively restricts the flexion and extension of cervical and thoracic vertebrae in mice, delaying spinal ligament ossification and reducing chronic secondary spinal cord injury.

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SurgeryMedical ImagingBioinformatics

Synthetic 3D Spinal Vertebrae Reconstruction from Biplanar X-rays Utilizing Generative Adversarial Networks

J. Pers. Med., 2023 • November 24, 2023

This study explores the use of a Generative Adversarial Network (GAN) to reconstruct 3D spinal vertebrae structures from synthetic biplanar X-ray images. The X2CT-GAN model was applied, focusing on an...

KEY FINDING: The GAN-based method can effectively reconstruct 3D spinal vertebrae structures from biplanar X-rays.

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SurgeryOrthopedicsSpinal Disorders

Anterior transcorporeal approach combined with posterior translaminar approach in percutaneous endoscopic cervical discectomy for two‑segment cervical disc herniation treatment: a technical report and early follow‑up

Journal of Orthopaedic Surgery and Research, 2024 • January 5, 2024

The study introduces a combined anterior transcorporeal and posterior translaminar approach for full endoscopic treatment of mixed-type two-segment cervical disc herniation (MTCDH). The technique aims...

KEY FINDING: Patients experienced significant symptom and pain reduction post-operatively, as indicated by clinical assessment scales.

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SurgeryOrthopedicsMusculoskeletal Medicine

Which Indicator Among Lumbar Vertebral Hounsfield Unit, Vertebral Bone Quality, or Dual-Energy X-Ray Absorptiometry-Measured Bone Mineral Density Is More Efficacious in Predicting Thoracolumbar Fragility Fractures?

Neurospine, 2023 • December 1, 2023

The study aimed to determine which indicator—lumbar vertebral Hounsfield units (HU), vertebral bone quality (VBQ), or bone mineral density (BMD)—is most effective in predicting thoracolumbar fragility...

KEY FINDING: Lumbar vertebral HU exhibited a positive correlation with BMD (p < 0.01).

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SurgeryBiomechanicsMusculoskeletal Medicine

Biomechanical Study of 3 Osteoconductive Materials Applied in Pedicle Augmentation and Revision for Osteoporotic Vertebrae: Allograft Bone Particles, Calcium Phosphate Cement, Demineralized Bone Matrix

Neurospine, 2023 • December 1, 2023

This study evaluated the biomechanical properties of pedicle screws augmented or revised with allograft bone particles (ABP), calcium phosphate cement (CPC), and demineralized bone matrix (DBM) in ost...

KEY FINDING: ABP, CPC, and DBM significantly enhanced biomechanical properties of the screws.

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Spinal Cord InjurySurgeryResearch Methodology & Design

Role of durotomy on function outcome, tissue sparing, inflammation, and tissue stiffness after spinal cord injury in rats

MedComm, 2024 • February 2, 2024

The study investigates the impact of early durotomy on functional recovery, tissue sparing, inflammation, and tissue stiffness after SCI in rats. Durotomy was performed 24 hours post-injury. Results s...

KEY FINDING: Durotomy significantly promoted the recovery of hindlimb locomotor function, as shown by improved BBB scores compared to laminectomy alone.

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SurgeryTraumaPublic Health

Enhancing Cranio-Maxillofacial Fracture Care in Low- and Middle-Income Countries: A Systematic Review

J. Clin. Med., 2024 • April 22, 2024

Cranio-maxillofacial (CMF) injuries pose a significant challenge in low- and middle-income countries (LMICs) due to inadequate infrastructure, resources, and training. Effective CMF fracture care in L...

KEY FINDING: The review highlights the crucial role of education and training for local surgeons in LMICs, emphasizing that it's the cornerstone for sustainable improvements in CMF care.

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Spinal Cord InjurySurgeryResearch Methodology & Design

Tracing the evolving dynamics and research hotspots of spinal cord injury and surgical decompression from 1975 to 2024: a bibliometric analysis

Frontiers in Neurology, 2024 • August 5, 2024

This study provides a comprehensive overview of research on SCI and surgical decompression over the past five decades using bibliometric analysis. The analysis identifies key trends, leading countries...

KEY FINDING: The USA and China are the leading countries in SCI and surgical decompression research, with the University of Toronto being the most prolific institution.

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ImmunologyGeneticsSurgery

Donor MHC-specific thymus vaccination allows for immunocompatible allotransplantation

Cell Research, 2025 • January 3, 2025

The study introduces a donor MHC-specific thymus vaccination (DMTV) strategy to induce T cell tolerance to both autologous and allogeneic donor MHC. DMTV involves expressing allogeneic MHC molecules i...

KEY FINDING: Ectopic expression of allogeneic MHC in the recipient thymus leads to stable expression in TECs and DCs.

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COVID-19SurgeryBrain Injury

The influence of government-issued lockdowns during the COVID-19 pandemic on traumatic brain injuries in Tyrol, Austria

Brain and Spine, 2025 • December 9, 2024

The study investigated the impact of COVID-19 lockdowns and restrictions on the incidence of traumatic brain injuries (TBI) in Tyrol, Austria, comparing TBI rates during lockdown periods in 2020 and 2...

KEY FINDING: During the first lockdown in the winter of 2020/2021, there was a notably lower incidence of moderate and severe TBIs compared to the corresponding period in 2019/2020 (p = 0.016).

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