Browse the latest research summaries in the field of rehabilitation for spinal cord injury patients and caregivers.
Showing 2,981-2,990 of 3,020 results
Frontiers in Neurology, 2022 • August 17, 2022
This review discusses the principles of ESWT, its cellular and molecular mechanisms, and its application in treating central and peripheral nervous system diseases based on animal and clinical studies...
KEY FINDING: ESWT can promote neural tissue regeneration and repairment in both the central and peripheral nervous systems, as demonstrated in animal studies of sciatic nerve injury, cerebral infarction, and spinal cord injury.
Acta Cir Bras, 2022 • August 1, 2022
This study investigated the impact of aerobic treadmill exercises on nerve regeneration following sciatic nerve injury and repair with a nerve graft in rats. The rats were divided into four groups: SH...
KEY FINDING: Functional analysis (SFI) did not show a statistical difference between the group grafted with (–50.94) and without exercise (-65.79) after 90 days.
Frontiers in Neuroscience, 2022 • December 7, 2022
In this study, we have characterized the modular structure of the locomotor network that the spinal cord is capable of producing. We identified modularity in response to the step-related sensory feedba...
KEY FINDING: Results for both NMF and ICA indicated that the subjects with SCI were similar among themselves, but expressed a greater variability in the number of synergies for criterion variance capture compared to NDs, and weaker correlation to NDs.
J Lasers Med Sci, 2022 • June 23, 2022
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons and accumulation of α-synuclein. Cell therapy, especially with MSCs, offers neuro...
KEY FINDING: Cell therapy, particularly using mesenchymal stem cells (MSCs), shows promise due to their self-renewal, differentiation, and immunomodulatory properties.
Cell Reports Medicine, 2023 • February 21, 2023
Roussel et al.1 provide new insight into mecencephalic locomotor region (MLR) stimulation to treat spinal cord injury in mice. Previously, it was unclear which part of the MLR to target. Now, evidence...
KEY FINDING: Excitatory CnF, but not PNN, stimulation correlated with spontaneous improvement in locomotor score over time.
Stem Cell Research & Therapy, 2023 • March 22, 2023
This study explored the effects of LIPUS stimulation on chondrogenic differentiation of hUC-MSCs, proliferation, and anti-inflammation of human chondrocyte C28/I2 cells. Rat knee articular cartilage d...
KEY FINDING: LIPUS stimulation effectively promoted the expression of mature cartilage-related genes and proteins and inhibited TNF-α gene expression in hUC-MSCs.
Frontiers in Medicine, 2023 • March 30, 2023
This review examines the effectiveness of exercise as a treatment for MS using EAE animal models, extracting data from various databases to assess the impacts of exercise on MS. The review infers that...
KEY FINDING: Exercise regimens can reduce the severity of clinical manifestations of EAE, including neurological signs, motor function, pain, and cognitive deficits.
Translational Neuroscience, 2023 • August 30, 2023
This study investigates the effects of γ-oryzanol on motor function recovery in mice after spinal cord injury (SCI). The mice were divided into sham, injury, and γ-oryzanol-treated groups, with the γ-...
KEY FINDING: γ-Oryzanol treatment improved gait following SCI, as shown by behavioral tests.
International Journal of Surgery, 2024 • September 26, 2023
This systematic review and network meta-analysis evaluated the effectiveness of nonpharmacological interventions for reducing psychological symptoms in patients with chronic low back pain (CLBP). The ...
KEY FINDING: Mind body therapy, biopsychosocial approach, and physical therapy were effective in reducing depression compared to the control group.
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2023 • August 17, 2023
The study aimed to investigate the effects of different pulse polarities of stimulus on movement patterns of bilateral hindlimbs and develop a gait function reconstruction training strategy. The exper...
KEY FINDING: Two special sites were identified in the lumbosacral spinal cord of rats that, when stimulated with ISMS, could activate the CPG neural network to induce alternating patterns in the hindlimbs.