Browse the latest research summaries in the field of rehabilitation for spinal cord injury patients and caregivers.
Showing 2,991-3,000 of 3,020 results
Biomedicines, 2023 • November 10, 2023
This retrospective study evaluated the efficacy and safety of intrasphincteric BoNT-A injections in patients with non-spinal cord injury-related detrusor sphincter dyssynergia (DSD). The primary outco...
KEY FINDING: There was a statistically significant reduction in maximum detrusor pressure (Pdetmax) after treatment (p = 0.006).
Science Advances, 2024 • February 28, 2024
This study investigates the capacity of skeletal muscles to act as biological amplifiers of neural information by surgically rewiring nerves with varying neural capacities to a target muscle. The resu...
KEY FINDING: Skeletal muscle can be reinnervated by a number of axons multiple times its initial physiological innervation.
Front. Rehabil. Sci., 2024 • March 27, 2024
This scoping review aimed to identify and evaluate the available evidence on assessments and interventions for body functions and structures to prepare adults with acute spinal cord SCI/D for activity...
KEY FINDING: SCIM III, ISNCSCI, and GRASSP version 2 can be used as assessments in the early phase after SCI/D.
Bioeng Transl Med, 2024 • May 1, 2024
This study investigates the efficacy of photobiomodulation (PBM) in promoting neuroregeneration and functional recovery after spinal cord injury (SCI) using both implantable (iPBM) and transcutaneous ...
KEY FINDING: Optimal neuroprotection in vitro was achieved with PBM between 4 and 22 mW/cm2, with 11 mW/cm2 for 1 min per day (0.66 J/cm2) increasing cell viability by 45% and neurite outgrowth by 25%.
Journal of Rehabilitation and Assistive Technologies Engineering, 2025 • January 1, 2025
This pilot study investigated the feasibility of using an end-effector robot-assisted gait trainer (E-RAGT) to help individuals with spinal cord injury or stroke reach recommended levels of exercise i...
KEY FINDING: Every participant was able to reach moderate-to-vigorous exercise intensity on the E-RAGT.
Scientific Reports, 2025 • January 29, 2025
This study uses a transcriptomic approach to investigate the mechanisms by which photobiomodulation (PBM) exerts its effects on spinal cord injury (SCI) in rats. The findings indicate that PBM promote...
KEY FINDING: PBM treatment resulted in 1275 differentially expressed genes (DEGs), with 397 upregulated and 878 downregulated, indicating a significant change in gene expression patterns after PBM.
Exp Neurol, 2015 • April 1, 2015
The study demonstrated that conditional genetic deletion of PTEN in mature cortical motoneurons can enable regenerative growth of CST axons after SCI. Enhanced regeneration, achieved by deleting PTEN,...
KEY FINDING: PTEN deletion in adult mice shortly post-SCI can enhance regenerative growth of CST axons.
PLoS ONE, 2016 • March 25, 2016
This study investigated whether remodeling of corticospinal tract (CST) terminals from the non-ischaemic hemisphere is associated with spontaneous recovery in rats with subcortical infarcts. Rats were...
KEY FINDING: Rats with subcortical infarcts exhibited sensorimotor deficits and impaired neurological function in the early phase after MCAO but recovered over time.
Journal of Exercise Rehabilitation, 2016 • July 31, 2016
This study investigated the effect of treadmill exercise on functional recovery of locomotion in relation with the expression of BDNF after spinal cord contusion injury in rats. The results showed tha...
KEY FINDING: SCI induced loss of locomotor function with decreased BDNF expression in the injury site.
Neural Regeneration Research, 2016 • December 1, 2016
This study investigated the effect of fine motor skill training on functional plasticity of the corticospinal tract after spinal cord injury in rats. The study found that fine motor skill training pro...
KEY FINDING: Functional recovery was better in the forelimbs and forepaws of trained rats compared with untrained rats after spinal cord injury.