Browse the latest research summaries in the field of regenerative medicine for spinal cord injury patients and caregivers.
Showing 241-250 of 2,298 results
Neural Regen Res, 2013 • June 1, 2013
This study investigated the use of aligned and randomly oriented collagen nanofiber scaffolds to regulate the biological behaviors of neural stem cells. The results indicated that novel nanofiber scaf...
KEY FINDING: The proliferation of spinal cord-derived neural stem cells on novel nanofiber scaffolds was obviously enhanced.
Neural Regen Res, 2013 • January 1, 2013
This study investigated the role of ATP-activated mTOR signaling in the physiology and pathology of SCI, with a special focus on molecular targets of upstream, downstream, and inhibitor of mTOR kinase...
KEY FINDING: ATP promotes locomotor recovery after spinal cord injury in rats, as demonstrated by improved BBB scores in the ATP group compared to control groups.
Neural Regeneration Research, 2013 • January 1, 2013
Following spinal cord injury, numerous endogenous Schwann cells migrate into the lesion site from the nerve roots, involving in the formation of repaired tissue and myelination of regenerating and dem...
KEY FINDING: Following spinal cord injury, endogenous Schwann cells invade the lesion site, involving in tissue repair and axonal regeneration and myelination.
Neural Regeneration Research, 2013 • August 1, 2013
This study investigates the protective effects of basic fibroblast growth factor (bFGF) on motor endplates after spinal cord injury in rats. The distal end of the spinal cord and neuromuscular junctio...
KEY FINDING: Basic fibroblast growth factor promotes the recovery of hindlimb locomotor function in rats with spinal cord injury.
Neural Regen Res, 2013 • August 1, 2013
This study investigates the temporal and spatial changes in the expression of protein disulfide isomerase A3, stress-induced-phosphoprotein 1 and heat shock cognate protein 70 in rabbit spinal cords a...
KEY FINDING: Hind limb function initially improves after spinal cord ischemia/reperfusion injury but deteriorates later.
Neural Regeneration Research, 2013 • August 1, 2013
This study investigated the effect of astragaloside IV on sciatic nerve regeneration in mice, finding that it promotes repair and functional recovery. Astragaloside IV treatment resulted in increased ...
KEY FINDING: Astragaloside IV accelerates nerve myelin sheath growth in mice with sciatic nerve injury and increases the diameter and number of myelinated nerve fibers.
Neural Regeneration Research, 2013 • October 1, 2013
This study evaluated the impact of olfactory ensheathing cell transplantation on sympathetic skin responses and ASIA scores in 43 patients with chronic spinal cord injury. The results showed significa...
KEY FINDING: Sympathetic skin response latency decreased significantly after olfactory ensheathing cell transplantation, indicating improved autonomic nerve function.
Neural Regen Res, 2013 • November 1, 2013
This study monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology. The results showed that the somatosensory evoked potential latency wa...
KEY FINDING: Somatosensory evoked potential latency was significantly prolonged during spinal cord ischemia, reflecting the degree of ischemic injury.
Neural Regen Res, 2013 • November 1, 2013
This study investigates the expression of substance P and calcitonin gene-related peptide in dorsal root ganglia of rats with sciatic nerve injury. A sciatic nerve defect model was created, and the ex...
KEY FINDING: Substance P and calcitonin gene-related peptide expression in dorsal root ganglia were altered over time in rats with sciatic nerve injury.
Neural Regen Res, 2013 • November 1, 2013
This study explores the use of diffusion tensor tractography to assess nerve root function in patients with radiculopathy induced by intervertebral disc degeneration. The research introduces a quantit...
KEY FINDING: Fiber bundles in affected nerve roots tend to gather together and are often interrupted compared to unaffected nerve roots.