Browse the latest research summaries in the field of pulmonology for spinal cord injury patients and caregivers.
Showing 51-60 of 155 results
The Journal of Spinal Cord Medicine, 2021 • January 1, 2021
This study investigated the association between high tidal volume ventilation (HVtV) and ventilator-associated pneumonia (VAP) in patients with acute cervical spinal cord injury (SCI). The study found...
KEY FINDING: HVtV was associated with a 1.96 relative risk of VAP development (95% credible interval 1.55–2.17) on Bayesian analysis.
The Journal of Spinal Cord Medicine, 2022 • January 1, 2020
This prospective study evaluated a surgical algorithm for ventilator weaning in ten patients with cervical tetraplegia, incorporating diaphragm pacing, phrenic nerve reconstruction, and diaphragm musc...
KEY FINDING: Patients who underwent pacemaker implantation alone or combined with phrenic nerve reconstruction showed promising results in ventilator weaning.
Asian Spine J, 2021 • December 1, 2021
The technical note presents a case of a 30-year-old male with posttraumatic tetraplegia and ventilator dependence following a C1–C2 spinal cord injury. Bilateral phrenic nerve stimulator electrodes we...
KEY FINDING: Diaphragm pacing with phrenic nerve stimulation facilitated weaning from mechanical ventilation and spontaneous ventilator-free breathing at 20 weeks post-implantation.
Exp Neurol, 2021 • August 1, 2021
This study evaluated the impact of a single session of acute intermittent hypoxia (AIH) on breathing capacity in adults with chronic spinal cord injury (SCI). The primary finding was that AIH increase...
KEY FINDING: A single AIH session significantly increased maximal inspiratory pressure (MIP) compared to a sham treatment in adults with SCI.
J Neurol Phys Ther, 2021 • July 1, 2021
This article discusses the rationale for using diaphragm pacing (DP) as a rehabilitative strategy, especially when combined with established respiratory interventions. It introduces a Respiratory Reha...
KEY FINDING: Early use of diaphragm pacing after cervical spinal cord injury can promote weaning from mechanical ventilation and minimize related complications.
The Journal of Spinal Cord Medicine, 2023 • June 18, 2021
The study reviews the cervical approach for implanting phrenic nerve/diaphragm pacers as a minimally invasive technique, comparing it to intrathoracic and sub-diaphragmatic approaches. Results from a ...
KEY FINDING: The cervical approach for diaphragm pacer implantation is the most minimally invasive technique.
Medicine, 2021 • August 6, 2021
This case report describes an 87-year-old man who developed dysphagia (difficulty swallowing) due to respiratory muscle paralysis after a cervical spinal cord injury (CSCI). High-flow nasal cannula (H...
KEY FINDING: HFNC oxygen therapy improved swallowing function in a patient with dysphagia related to respiratory muscle paralysis following CSCI.
Journal of Neurotrauma, 2021 • December 15, 2021
This study demonstrates that low-dose ampakine treatment can effectively increase diaphragm EMG activity after cervical SCI in rats, suggesting a potential pharmacological strategy for respiratory reh...
KEY FINDING: Both CX717 and CX1739 increased diaphragm EMG output ipsilateral to C2Hx during both baseline breathing and acute respiratory challenge at 4 days post-injury.
The Journal of Spinal Cord Medicine, 2022 • June 23, 2021
This case report presents an atypical clinical course of bulbar-ALS, characterized by isolated pulmonary recovery after stopping edaravone, despite continued systemic neurologic decline. The findings ...
KEY FINDING: A patient with late-stage bulbar ALS experienced a dramatic improvement in pulmonary function (FVC) after discontinuing edaravone treatment.
Annals of Rehabilitation Medicine, 2021 • December 31, 2021
This study investigated the relationship between pulmonary function parameters and dysphagia in individuals with cervical spinal cord injuries (CSCIs). The study found a significant correlation betwee...
KEY FINDING: Individuals with a history of tracheostomy, anterior surgical approach, and higher neurological level of injury had significantly more penetration-aspiration or pharyngeal residue.