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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pulmonology Research

Browse the latest research summaries in the field of pulmonology for spinal cord injury patients and caregivers.

Showing 51-60 of 155 results

Spinal Cord InjuryCritical CarePulmonology

High tidal volume ventilation is associated with ventilator-associated pneumonia in acute cervical spinal cord injury

The Journal of Spinal Cord Medicine, 2021 • January 1, 2021

This study investigated the association between high tidal volume ventilation (HVtV) and ventilator-associated pneumonia (VAP) in patients with acute cervical spinal cord injury (SCI). The study found...

KEY FINDING: HVtV was associated with a 1.96 relative risk of VAP development (95% credible interval 1.55–2.17) on Bayesian analysis.

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Spinal Cord InjuryPulmonologySurgery

Prospective analysis of a surgical algorithm to achieve ventilator weaning in cervical tetraplegia

The Journal of Spinal Cord Medicine, 2022 • January 1, 2020

This prospective study evaluated a surgical algorithm for ventilator weaning in ten patients with cervical tetraplegia, incorporating diaphragm pacing, phrenic nerve reconstruction, and diaphragm musc...

KEY FINDING: Patients who underwent pacemaker implantation alone or combined with phrenic nerve reconstruction showed promising results in ventilator weaning.

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Spinal Cord InjuryPulmonologyRehabilitation

Thirty-Six-Month Follow-up of Diaphragm Pacing with Phrenic Nerve Stimulation for Ventilator Dependence in Traumatic Tetraplegia: The Way Forward for Spinal Cord Injury Rehabilitation in a Developing Country

Asian Spine J, 2021 • December 1, 2021

The technical note presents a case of a 30-year-old male with posttraumatic tetraplegia and ventilator dependence following a C1–C2 spinal cord injury. Bilateral phrenic nerve stimulator electrodes we...

KEY FINDING: Diaphragm pacing with phrenic nerve stimulation facilitated weaning from mechanical ventilation and spontaneous ventilator-free breathing at 20 weeks post-implantation.

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Spinal Cord InjuryPulmonologyPhysiology

Single-session effects of acute intermittent hypoxia on breathing function after human spinal cord injury

Exp Neurol, 2021 • August 1, 2021

This study evaluated the impact of a single session of acute intermittent hypoxia (AIH) on breathing capacity in adults with chronic spinal cord injury (SCI). The primary finding was that AIH increase...

KEY FINDING: A single AIH session significantly increased maximal inspiratory pressure (MIP) compared to a sham treatment in adults with SCI.

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Spinal Cord InjuryPulmonology

Diaphragm Pacing and a Model for Respiratory Rehabilitation after Spinal Cord Injury

J Neurol Phys Ther, 2021 • July 1, 2021

This article discusses the rationale for using diaphragm pacing (DP) as a rehabilitative strategy, especially when combined with established respiratory interventions. It introduces a Respiratory Reha...

KEY FINDING: Early use of diaphragm pacing after cervical spinal cord injury can promote weaning from mechanical ventilation and minimize related complications.

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Spinal Cord InjuryPulmonologyNeurology

Diaphragm pacing using the minimally invasive cervical approach

The Journal of Spinal Cord Medicine, 2023 • June 18, 2021

The study reviews the cervical approach for implanting phrenic nerve/diaphragm pacers as a minimally invasive technique, comparing it to intrathoracic and sub-diaphragmatic approaches. Results from a ...

KEY FINDING: The cervical approach for diaphragm pacer implantation is the most minimally invasive technique.

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PulmonologyNeurologyRehabilitation

High-flow nasal cannula oxygen therapy was effective for dysphagia associated with respiratory muscle paralysis due to cervical spinal cord injury

Medicine, 2021 • August 6, 2021

This case report describes an 87-year-old man who developed dysphagia (difficulty swallowing) due to respiratory muscle paralysis after a cervical spinal cord injury (CSCI). High-flow nasal cannula (H...

KEY FINDING: HFNC oxygen therapy improved swallowing function in a patient with dysphagia related to respiratory muscle paralysis following CSCI.

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Spinal Cord InjuryPharmacologyPulmonology

Ampakines Stimulate Diaphragm Activity after Spinal Cord Injury

Journal of Neurotrauma, 2021 • December 15, 2021

This study demonstrates that low-dose ampakine treatment can effectively increase diaphragm EMG activity after cervical SCI in rats, suggesting a potential pharmacological strategy for respiratory reh...

KEY FINDING: Both CX717 and CX1739 increased diaphragm EMG output ipsilateral to C2Hx during both baseline breathing and acute respiratory challenge at 4 days post-injury.

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PulmonologyNeurology

Isolated pulmonary recovery in a veteran with late stage bulbar ALS following edaravone treatment and cessation

The Journal of Spinal Cord Medicine, 2022 • June 23, 2021

This case report presents an atypical clinical course of bulbar-ALS, characterized by isolated pulmonary recovery after stopping edaravone, despite continued systemic neurologic decline. The findings ...

KEY FINDING: A patient with late-stage bulbar ALS experienced a dramatic improvement in pulmonary function (FVC) after discontinuing edaravone treatment.

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Spinal Cord InjuryPulmonologyRehabilitation

Utilizing Pulmonary Function Parameters to Predict Dysphagia in Individuals With Cervical Spinal Cord Injuries

Annals of Rehabilitation Medicine, 2021 • December 31, 2021

This study investigated the relationship between pulmonary function parameters and dysphagia in individuals with cervical spinal cord injuries (CSCIs). The study found a significant correlation betwee...

KEY FINDING: Individuals with a history of tracheostomy, anterior surgical approach, and higher neurological level of injury had significantly more penetration-aspiration or pharyngeal residue.

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