Browse the latest research summaries in the field of pulmonology for spinal cord injury patients and caregivers.
Showing 151-155 of 155 results
JOURNAL OF NEUROTRAUMA, 2020 • February 1, 2020
The study investigates the effect of a PTPr inhibitory peptide on respiratory neuronal plasticity and functional restoration using a rat model of C2 hemisection SCI. The PTPr peptide was applied local...
KEY FINDING: PTPr peptide significantly improved ipsilateral hemidiaphragm function, as assessed in vivo with electromyography recordings.
ENEURO, 2019 • August 19, 2019
This study investigated the effect of promoting axon regeneration on respiratory function after cervical spinal cord injury (SCI) in rats. Systemic administration of a PTEN antagonist peptide (PAP4) p...
KEY FINDING: Systemic administration of PAP4 promoted significant functional recovery of diaphragmatic respiratory function after cervical SCI.
Neurobiol Dis, 2021 • January 1, 2021
This study investigates the effects of a novel LAR inhibitory peptide on respiratory function after cervical spinal cord injury (SCI) in rats. The results demonstrate that LAR peptide promotes recover...
KEY FINDING: LAR peptide significantly improved ipsilateral hemidiaphragm function, as assessed in vivo with electromyography recordings.
Frontiers in Molecular Neuroscience, 2009 • October 30, 2009
Loss of respiratory function is one of the leading causes of death following spinal cord injury. With the emergence of new and powerful tools from molecular neuroscience, new therapeutically relevant ...
KEY FINDING: Pharmacological intervention which can increase central respiratory drive might be a potential way to induce recovery of the ipsilateral hemidiaphragm following C2 hemisection – without contralateral phrenicotomy.
Journal of Inflammation, 2010 • October 25, 2010
This study investigates the in vivo immuno-regulatory effectiveness of human mesenchymal stem cells (hMSCs) using an ovalbumin challenge model of acute asthma in mice. The results demonstrate a direct...
KEY FINDING: hMSCs are well tolerated in the murine model of acute asthma, suggesting that hMSCs can favorably change the outcome of asthmatic inflammation without the pathology associated with cross-species application.