Pain Management Research

KEY FINDING: There were no adverse events in physical condition, laboratory data, or lumbar X-rays after injection, suggesting that PRP intradiscal injection is safe.

KEY FINDING: The study confirmed a higher occurrence of CRPS in females. The hand and wrist were the most commonly affected areas, followed by the ankle and foot.

KEY FINDING: HBOT and TAK-242 alleviated behavioral signs of CIPN, specifically mechanical allodynia and thermal hyperalgesia, in rats treated with paclitaxel and LPS.

KEY FINDING: The Gel-Cur-M exhibited superior functions compared to Gel and Cur-M alone, which includes ameliorating hyperalgesia while simultaneously improving locomotor and muscular functions after the nerve injury.

KEY FINDING: hASCs combined with heparin-based hydrogel micropatches enhanced nerve regeneration in a neuropathic pain animal model.

KEY FINDING: High-intensity swimming (HIS), but not low-intensity swimming (LIS), significantly alleviated mechanical and thermal hyperalgesia in CPIP mice.

KEY FINDING: Autologous blood products like platelet-rich plasma are safe and effective in stimulating the body’s regenerative responses for musculoskeletal pain.

KEY FINDING: NETs accumulate in the spinal cord during inflammatory pain, exacerbating neuroinflammation.

KEY FINDING: Mind body therapy, biopsychosocial approach, and physical therapy were effective in reducing depression compared to the control group.

KEY FINDING: Intravenous administration of RIPCs was most effective in reducing thermal hyperalgesia and mechanical allodynia in rats with neuropathic pain.