Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 481-490 of 682 results
Neurorehabilitation and Neural Repair, 2017 • April 1, 2017
The article addresses the discrepancy between basic science and clinical research regarding the interaction of pain and motor recovery after spinal cord injury (SCI). It highlights that while animal s...
KEY FINDING: Nociceptive input can have long-term effects on motor recovery after spinal cord injury by modulating the ability of the spinal cord to learn.
Trials, 2016 • November 15, 2016
The EN-PENS trial is a single-site, blinded, randomised controlled parallel-group superiority add-on trial with a 1:1 allocation ratio. Seventy-six patients will be randomised to receive either active...
KEY FINDING: The primary outcome is average 24-h pain intensity recorded on an 11-point numerical rating scale, averaged over the last 7 days of treatment.
CMAJ, 2017 • January 16, 2017
Neuropathic pain is a frequent complication of spinal cord injury that can significantly impair a patient's quality of life and ability to participate in daily activities. The CanPain SCI clinical pra...
KEY FINDING: The CanPain SCI clinical practice guideline is a valuable resource for clinicians treating neuropathic pain in patients after spinal cord injury.
JOURNAL OF NEUROTRAUMA, 2017 • November 1, 2017
This study demonstrates that the Rat Grimace Scale (RGS) can be effectively used to assess supraspinal pain sensation in rats following cervical spinal cord injury (SCI). The RGS was found to be sensi...
KEY FINDING: Rats with spinal cord injuries showed significantly higher RGS scores at week 5 post-injury compared to baseline and control groups, suggesting spontaneous neuropathic pain.
Journal of Pain Research, 2015 • September 8, 2015
This case report describes a 59-year-old female with chronic migraines who experienced complete resolution of her headaches after starting low-dose intrathecal ziconotide. The patient had previously t...
KEY FINDING: The patient experienced complete resolution of migraine headaches following the initiation of low-dose intrathecal ziconotide (1 µg/day).
BMC Neurology, 2015 • September 29, 2015
The aim of the study was to investigate the putative mechanism of neurofeedback training on central neuropathic pain and its underlying brain signatures in patients with chronic paraplegia. Neurofeedb...
KEY FINDING: Six out of seven patients reported immediate reduction of pain during neurofeedback training.
Annals of Rehabilitation Medicine, 2015 • October 1, 2015
This study aimed to determine the effect of pulsed radiofrequency (PRF) applied to the sciatic nerve on neuropathic pain in a chronic constriction injury (CCI) rat model. The results indicated that PR...
KEY FINDING: After PRF, withdrawal frequency decreased and withdrawal latency prolonged over time in group B, indicating reduced pain sensitivity.
Neuromodulation, 2016 • January 1, 2016
This retrospective study examined the incidence of spinal cord injury (SCI) following spinal cord stimulation (SCS) implantation using percutaneous and paddle electrodes between 2000 and 2009. The stu...
KEY FINDING: The overall incidence of SCI was 2.13% in patients undergoing SCS implantation.
Spinal Cord Series and Cases, 2016 • October 27, 2016
This case report investigated the effects of brain–computer interface (BCI) training on persistent neuropathic pain (NP) after cervical spinal cord injury (SCI). The patient underwent BCI training as ...
KEY FINDING: BCI training increased event-related desynchronization (ERD) in the patient's brain activity, indicating enhanced motor cortex excitability.
Scientific Reports, 2016 • January 6, 2016
This study shows distinct association of below-level NP with structural changes of the spinal cord and brain after SCI. In individuals with paraplegia, the reduction in SCA was associated with below-l...
KEY FINDING: Individuals with SCI exhibited decreased cord area, reduced grey matter (GM) volumes in anterior cingulate cortex (ACC), left insula, left secondary somatosensory cortex, bilateral thalamus, and decreased white matter volumes in pyramids and left internal capsule.