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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 471-480 of 682 results

NeurologyPain ManagementRehabilitation

Extracorporeal Shock Wave Therapy for Painful Chronic Neurogenic Heterotopic Ossification After Traumatic Brain Injury: A Case Report

Ann Rehabil Med, 2015 • April 1, 2015

This case report describes the use of extracorporeal shock wave therapy (ESWT) to treat a 72-year-old male with painful chronic neurogenic heterotopic ossification (NHO) following a traumatic brain in...

KEY FINDING: ESWT resulted in pain relief, as measured by a decrease in VAS scores from 8-10 to 3, which was maintained throughout the 12-week follow-up period.

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AnesthesiologyNeurologyPain Management

Association between extracellular signal-regulated kinase expression and the anti-allodynic effect in rats with spared nerve injury by applying immediate pulsed radiofrequency

BMC Anesthesiology, 2015 • May 29, 2015

This study evaluated the analgesic effect of immediate pulsed radiofrequency (PRF) treatment after nerve injury in a rat model of spared nerve injury (SNI). The results showed that immediate PRF appli...

KEY FINDING: Immediate PRF treatment after SNI significantly reduced mechanical and cold allodynia in rats over 28 days.

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NeurologyPain Management

Spinal cord stimulation modulates supraspinal centers of the descending antinociceptive system in rats with unilateral spinal nerve injury

Mol Pain, 2015 • June 11, 2015

This study investigated the involvement of serotonergic and noradrenergic pathways in spinal cord stimulation (SCS)-induced antinociception in rats with spinal nerve injury. The researchers found that...

KEY FINDING: SCS increased the number of serotonergic neurons and activated them in the DRN, suggesting a key role for this area in SCS-induced pain relief.

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Spinal Cord InjuryNeurologyPain Management

A novel nonpharmacological intervention – breathing-controlled electrical stimulation for neuropathic pain management after spinal cord injury – a preliminary study

Journal of Pain Research, 2016 • November 3, 2016

This study investigated the effectiveness of breathing-controlled electrical stimulation (BreEStim) for neuropathic pain management in spinal cord injury (SCI) patients, comparing it to conventional e...

KEY FINDING: BreEStim showed significantly greater analgesic effects compared to EStim. Reduction in VAS score was significantly greater after BreEStim (2.6±0.3) than after EStim (0.8±0.3) (P<0.001).

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NeurologyPain ManagementRehabilitation

Botulinum Toxin Type A for the Treatment of Neuropathic Pain in Neuro-Rehabilitation

Toxins, 2015 • June 30, 2015

This review examines the effectiveness of botulinum toxin type A (BTX-A) in treating neuropathic pain (NP) associated with neurological conditions commonly managed in neuro-rehabilitation settings. BT...

KEY FINDING: BTX-A has shown promise in treating neuropathic pain associated with various neurological disorders, including post-stroke shoulder pain and painful diabetic neuropathy.

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Pain ManagementRehabilitation

Effect of Exercise on μ-Opioid Receptor Expression in the Rostral Ventromedial Medulla in Neuropathic Pain Rat Model

Ann Rehabil Med, 2015 • June 1, 2015

This study aimed to determine the effects of aerobic exercise on neuropathic pain and whether regular treadmill exercise alters μ-opioid receptor (MOR) expression in the rostral ventral medulla (RVM) ...

KEY FINDING: Regular treadmill exercise led to a decrease in body weight in the CCI+exercise group compared to the CCI group.

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NeurologyPain ManagementOrthopedics

The Role of the Peripheral and Central Nervous Systems in Rotator Cuff Disease

J Shoulder Elbow Surg, 2015 • August 1, 2015

The review identifies a number of neural structures and mechanisms that may contribute to pain and shoulder dysfunction in patients with RC disease, including proprioceptive function disruption and al...

KEY FINDING: RC disease is associated with structural and functional alterations of proprioceptors. Either reduced or inconsistent proprioceptive information from the injured muscle-tendon unit and altered muscle reflex activity may impair shoulder proprioception and contribute to impaired kinematics and muscle recruitment.

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Spinal Cord InjuryPain ManagementRehabilitation

Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?

Case Reports in Medicine, 2015 • July 15, 2015

This case report describes a patient with spinal cord injury-related neuropathic pain who experienced complete pain relief with baclofen 5% cream. However, the pain relief led to increased walking dif...

KEY FINDING: Topical baclofen 5% cream can effectively control neuropathic pain associated with spinal cord injury.

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NeurologyPain Management

Effects of combined electrical stimulation of the dorsal column and dorsal roots on wide-dynamic range neuronal activity in nerve-injured rats

Neuromodulation, 2015 • October 1, 2015

This study examined whether combining electrical stimulation of the dorsal column (DC) and dorsal root (DR) provides a greater inhibitory effect on wide-dynamic-range (WDR) neurons in nerve-injured ra...

KEY FINDING: At a moderate intensity of electrical stimulation, different patterns of conditioning stimulation (CS) all reduced the C-component of WDR neurons in response to electrical stimuli and inhibited windup.

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Spinal Cord InjuryPain ManagementRehabilitation

Lumbar Epidural Steroid Injection for Painful Spasticity in Cervical Spinal Cord Injury: A Case Report

Ann Rehabil Med, 2015 • August 19, 2015

This case report describes a 53-year-old male with cervical spinal cord injury (SCI) who suffered from severe pain and spasticity in his lower limbs, hindering his ability to stand and walk. Following...

KEY FINDING: A patient with cervical SCI experienced significant reduction in lower limb spasticity and pain after lumbar ESI.

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