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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 321-330 of 682 results

NeurologyPain ManagementBiomedical

A Fully Implantable Miniaturized Liquid Crystal Polymer (LCP)-Based Spinal Cord Stimulator for Pain Control

Sensors, 2022 • January 10, 2022

This study introduces a fully implantable, miniaturized spinal cord stimulator based on liquid crystal polymer (LCP) for pain control. The device addresses limitations of conventional metal-packaged s...

KEY FINDING: The LCP-based spinal cord stimulator effectively suppressed pain in a rat model of spared nerve injury.

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Spinal Cord InjuryPain Management

The demographics of pain after spinal cord injury: a survey of our model system

Spinal Cord Series and Cases, 2022 • January 14, 2022

This survey-based study investigates the demographics of pain following spinal cord injury (SCI), utilizing standardized pain assessment tools to characterize pain types and severities in relation to ...

KEY FINDING: 81% of individuals with SCI experience chronic pain, and 86% of those with pain have neuropathic pain.

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Spinal Cord InjuryPain ManagementResearch Methodology & Design

The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update

Spinal Cord, 2022 • February 5, 2022

The objective was to update the 2016 version of the Canadian clinical practice guidelines for the management of neuropathic pain in people with spinal cord injury (SCI). The working group identified an...

KEY FINDING: The panel agreed on three new screening and diagnosis recommendations, and eight new treatment recommendations. No new model of care recommendations were proposed as no relevant articles were identified.

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NeurologyPain ManagementRehabilitation

Non-invasive Brain Stimulation for Neuropathic Pain After Spinal Cord Injury: A Systematic Review and Network Meta-Analysis

Frontiers in Neuroscience, 2022 • February 11, 2022

This systematic review and network meta-analysis evaluated the effect of non-invasive brain stimulation (NIBS) on neuropathic pain (NP) after spinal cord injury (SCI) and compared the effects of two d...

KEY FINDING: NIBS can reduce the pain score in patients with neuropathic pain after spinal cord injury. The meta-analysis showed that the pain score of the NIBS group was lower than that of the control group.

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Spinal Cord InjuryNeurologyPain Management

Efficacy of transcutaneous electrical nerve stimulation in people with pain after spinal cord injury: a meta-analysis

Spinal Cord, 2022 • March 11, 2022

This meta-analysis evaluated the efficacy of TENS for pain relief in individuals with SCI, incorporating data from six studies. The results indicate that TENS can improve pain symptoms, as evidenced b...

KEY FINDING: TENS was found to significantly reduce pain as measured by the visual analog scale (VAS) in patients with spinal cord injury.

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Spinal Cord InjuryNeurologyPain Management

Effects of repeated transcranial magnetic stimulation in the dorsolateral prefrontal cortex versus motor cortex in patients with neuropathic pain after spinal cord injury: a study protocol

BMJ Open, 2022 • January 1, 2022

This study protocol outlines a clinical trial comparing rTMS in the DLPFC versus M1 for neuropathic pain after SCI. The study will recruit 50 participants and assess pain, sleep, and anxiety levels ov...

KEY FINDING: The study is designed to compare the efficacy of rTMS on the DLPFC with the motor cortex (M1) in NPP after SCI.

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Pain ManagementResearch Methodology & Design

The Use of Conditioning Open-Label Placebo in Opioid Dose Reduction: A Case Report and Literature Review

Frontiers in Pain Research, 2021 • July 12, 2021

This case report explores the use of conditioning open-label placebo (COLP) as a pharmaco-behavioral intervention to reduce opioid dosage and side effects after inpatient rehabilitation discharge. The...

KEY FINDING: The patient could discontinue oxycodone intake (a reduction from 15 morphine equivalents/day) after rehabilitation discharge following COLP treatment.

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Pain ManagementRehabilitation

Physiotherapy interventions may relieve pain in individuals with central neuropathic pain: a systematic review and meta-analysis of randomised controlled trials

Therapeutic Advances in Chronic Disease, 2022 • January 12, 2022

This systematic review and meta-analysis evaluated the effectiveness of physiotherapy interventions for managing central neuropathic pain (cNeP) from any cause. The study included 23 randomised contro...

KEY FINDING: Non-invasive neurostimulation was found to reduce pain severity due to spinal cord injury and phantom limb pain.

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NeurologyPain Management

Involvement of Opioid Peptides in the Analgesic Effect of Spinal Cord Stimulation in a Rat Model of Neuropathic Pain

Neurosci. Bull., 2022 • April 9, 2022

This study characterized the analgesic effect of spinal cord stimulation (SCS) in a rat model of neuropathic pain, focusing on the involvement of opioid peptides. The study explored the impact of sti...

KEY FINDING: The analgesic effect of SCS is more effective in rats with moderate, rather than severe, mechanical hypersensitivity.

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Spinal Cord InjuryPain ManagementRehabilitation

Long-term physical therapy for neuropathic pain after cervical spinal cord injury and resting state electroencephalography: a case report

Spinal Cord Series and Cases, 2022 • March 29, 2022

This case report investigated the long-term effects of physical therapy, including intensive gait training, on neuropathic pain and peak alpha frequency (PAF) in a patient with cervical spinal cord in...

KEY FINDING: NRS scores for the mean and maximum intensities of pain decreased significantly after 6 weeks of physical therapy.

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