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  4. Physiotherapy interventions may relieve pain in individuals with central neuropathic pain: a systematic review and meta-analysis of randomised controlled trials

Physiotherapy interventions may relieve pain in individuals with central neuropathic pain: a systematic review and meta-analysis of randomised controlled trials

Therapeutic Advances in Chronic Disease, 2022 · DOI: 10.1177/20406223221078672 · Published: January 12, 2022

Pain ManagementRehabilitation

Simple Explanation

This systematic review and meta-analysis aimed to evaluate the effectiveness of physiotherapy interventions for the management of central neuropathic pain (cNeP) due to any underlying cause. The review included randomised controlled trials that compared physiotherapy interventions to a control condition on pain among people with cNeP. The study found evidence supporting the use of non-invasive neurostimulation, acupuncture, TENS, mirror therapy and exercise for pain management in specific conditions causing cNeP.

Study Duration
Not specified
Participants
23 randomised controlled trials
Evidence Level
Systematic review and meta-analysis of randomised controlled trials

Key Findings

  • 1
    Non-invasive neurostimulation was found to reduce pain severity due to spinal cord injury and phantom limb pain.
  • 2
    Acupuncture was found to reduce pain severity among individuals with stroke.
  • 3
    Exercise was found to significantly reduce pain among people with multiple sclerosis.

Research Summary

This systematic review and meta-analysis evaluated the effectiveness of physiotherapy interventions for managing central neuropathic pain (cNeP) from any cause. The study included 23 randomised controlled trials and found that non-invasive neurostimulation reduced pain in spinal cord injury and phantom limb pain. Acupuncture, TENS, mirror therapy, and exercise also showed benefits for pain management in stroke, multiple sclerosis, and phantom limb pain, respectively.

Practical Implications

Clinical Practice

Physiotherapists can consider non-invasive neurostimulation for patients with SCI and phantom limb pain.

Research

Further research is needed to validate the benefits of non-invasive neurostimulation for stroke patients.

Guidelines

Clinical guidelines for cNeP management should consider including acupuncture, TENS and mirror therapy.

Study Limitations

  • 1
    Heterogeneity among studies
  • 2
    Limited number of studies for certain conditions
  • 3
    Restriction to randomised controlled trials

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