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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 331-340 of 682 results

Spinal Cord InjuryPain Management

Translation, cross-cultural adaptation, and analysis of the measurement properties of the Brazilian Portuguese version of the spinal cord injury pain instrument

Spinal Cord, 2022 • April 12, 2022

The study successfully translated and adapted the SCIPI for use in Brazil. The adapted SCIPI demonstrated strong reliability and validity in assessing neuropathic pain among individuals with spinal co...

KEY FINDING: The Brazilian version of the SCIPI demonstrated adequate structural validity, confirming its one-dimensional structure.

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Spinal Cord InjuryAssistive TechnologyPain Management

An Exploratory EEG Analysis on the Effects of Virtual Reality in People with Neuropathic Pain Following Spinal Cord Injury

Sensors, 2022 • March 29, 2022

This study investigates the impact of virtual reality (VR) on neuropathic pain (NP) in individuals with spinal cord injury (SCI) by analyzing changes in brain activity using electroencephalography (EE...

KEY FINDING: There was an increase in delta activity in frontal regions for 3D VR with a decrease in theta activity.

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Alternative MedicineNeurologyPain Management

Analgesia with 5’ extracellular nucleotidase-mediated electroacupuncture for neuropathic pain

Arq Neuropsiquiatr, 2022 • March 1, 2022

The study investigates the mechanism by which electroacupuncture (EA) provides analgesia for neuropathic pain, focusing on the role of ecto-5’-nucleotidase (5’-NT). Results indicate that EA upregulate...

KEY FINDING: Electroacupuncture (EA) increases the expression of ecto-5’-nucleotidase (5’-NT) in the spinal cord of rats with chronic constriction injury (CCI).

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Alternative MedicineNeurologyPain Management

Nrf2 Activation Mediates Antiallodynic Effect of Electroacupuncture on a Rat Model of Complex Regional Pain Syndrome Type-I through Reducing Local Oxidative Stress and Inflammation

Oxidative Medicine and Cellular Longevity, 2022 • February 14, 2022

The study aimed to explore the mechanisms through which EA ameliorates pain in a rat CRPS-I model, focusing on potential substances or biological processes affected during CRPS-I. The research identif...

KEY FINDING: Oxidative stress primarily occurs in local hindpaw tissues of CPIP rats and contributes to mechanical allodynia.

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Spinal Cord InjuryMental HealthPain Management

Pain, Mental Health, Life Satisfaction, and Understanding From Others in Veterans With Spinal Cord Injury

Rehabil Psychol, 2022 • August 1, 2022

This study examined the relationships among pain, mental health symptom severity, life satisfaction, and understanding from others in veterans with SCI. The findings indicated that pain and understand...

KEY FINDING: Pain was significantly associated with increased mental health symptom severity in veterans with SCI.

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Alternative MedicineImmunologyPain Management

Z-Guggulsterone Relieves Neuropathic Pain by Inhibiting the Expression of Astrocytes and ProinflammatoryCytokines in theSpinal Dorsal Horn

Journal of Pain Research, 2022 • May 5, 2022

This study demonstrated that Z-guggulsterone significantly alleviated mechanical and thermal hyperalgesia induced by CCI in mice. The study observed that Z-guggulsterone inhibited astrocytes activatio...

KEY FINDING: Z-guggulsterone significantly reduced mechanical and thermal hyperalgesia (increased sensitivity to pain) in mice with CCI.

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Mental HealthPain ManagementRehabilitation

The cognitive-behavioral aspects of the Mulligan concept of manual therapy: A systematic review

Eur J Transl Myol, 2022 • May 5, 2022

This systematic review aimed to evaluate the biopsychosocial effects of the Mulligan Concept (MC) of manual therapy (MT) on patients with low back pain (LBP). The review included six studies and found...

KEY FINDING: Studies applying the Mulligan Concept of Manual Therapy to treat Low Back Pain often lacked concern for the intervention's effect on cognitive and behavioral parameters.

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Spinal Cord InjuryPain ManagementRehabilitation

Frequency of neuropathic pain and its effects on rehabilitation outcomes, balance function and quality of life among people with traumatic spinal cord injury

Pak J Med Sci, 2022 • March 1, 2022

The study investigated the frequency and impact of neuropathic pain on rehabilitation outcomes, balance function, and quality of life in patients with traumatic spinal cord injury. A cross-sectional s...

KEY FINDING: The study found that a significant majority (70.73%) of traumatic SCI patients experienced neuropathic pain.

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NeurologyPain ManagementGenetics

Spinal Cord Stimulation Alleviates Neuropathic Pain by Attenuating Microglial Activation via Reducing Colony-Stimulating Factor 1 Levels in the Spinal Cord in a Rat Model of Chronic Constriction Injury

Anesth Analg, 2022 • July 1, 2022

This study demonstrates that spinal cord stimulation (SCS) can alleviate neuropathic pain in rats by inhibiting the transmission of colony-stimulating factor 1 (CSF1) from the dorsal root ganglion (DR...

KEY FINDING: SCS significantly increased the mechanical withdrawal threshold in CCI rats, indicating pain relief.

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Spinal Cord InjuryNeurologyPain Management

Phenotypes of Motor Deficit and Pain after Experimental Spinal Cord Injury

Bioengineering, 2022 • June 20, 2022

The study examines motor deficits and pain phenotypes in rats after experimental spinal cord injury (SCI), monitoring them for up to 5 months to understand the impact of injury severity and age on mot...

KEY FINDING: Motor dysfunction remained persistent after a moderate SCI in older animals (5-month-old).

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