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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 231-240 of 682 results

Spinal Cord InjuryAlternative MedicinePain Management

Feasibility of using remotely delivered Spring Forest Qigong to reduce neuropathic pain in adults with spinal cord injury: a pilot study

Front. Physiol., 2023 • August 31, 2023

This study investigated the feasibility and potential efficacy of remotely delivered Spring Forest Qigong for reducing neuropathic pain in adults with spinal cord injury (SCI). The results demonstrate...

KEY FINDING: Remote Spring Forest Qigong is feasible for adults with SCI-related neuropathic pain, with high adherence and no study-related adverse events.

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Alternative MedicineNeurologyPain Management

The Serotonin-Mediated Anti-Allodynic Effect of Yokukansan on Paclitaxel-Induced Neuropathic Pain

Medicina, 2024 • February 21, 2024

This study investigated the anti-allodynic effect of Yokukansan (YKS) on Paclitaxel-induced neuropathic pain in rats. The results showed that YKS significantly enhanced the withdrawal threshold in PTX...

KEY FINDING: YKS administration significantly enhanced the withdrawal threshold in PTX rats, indicating a reduction in pain sensitivity.

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Spinal Cord InjuryPatient ExperiencePain Management

Development of a pain self-management intervention framework for people with spinal cord injury

African Journal of Primary Health Care & Family Medicine, 2023 • October 26, 2023

This study developed a pain self-management intervention framework for PWSCI using a modified e-Delphi method with a panel of experts. The framework includes 56 interventions spanning medical, psychol...

KEY FINDING: The final pain self-management framework consists of 56 interventions, encompassing medical, psychological, therapeutic, and social approaches.

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Spinal Cord InjuryNeurologyPain Management

Comparison of intermittent theta burst stimulation and high-frequency repetitive transcranial magnetic stimulation on spinal cord injury-related neuropathic pain: A sham-controlled study

The Journal of Spinal Cord Medicine, 2025 • November 17, 2023

This study investigated the effects of iTBS and high-frequency rTMS on SCI-related neuropathic pain compared to a sham control group. The results showed that both real iTBS and real rTMS significantly...

KEY FINDING: Both real iTBS and real rTMS significantly reduced pain compared to the sham rTMS group, according to all pain evaluation tools used.

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Pain ManagementPediatricsRehabilitation

Pain Management Strategies for Botulinum Toxin Type A Injections in Children: A Comprehensive National Survey and Procedural Protocol

Cureus, 2023 • November 5, 2023

The study aimed to delineate the national landscape concerning pain management for botulinum toxin type A injections in pediatric patients and to formulate a protocol grounded in current scientific ev...

KEY FINDING: There is a concern among specialists about managing pain caused by BoNT-A injections in children.

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Spinal Cord InjuryPain ManagementOrthopedics

A Comparison of Neuropathic Pain Experiences Among Paralympic Versus Recreational Athletes with Spinal Cord Injury

Sports Medicine - Open, 2023 • October 8, 2023

This study compared neuropathic pain experiences among Paralympic versus recreational athletes with SCI, finding that Paralympic athletes reported greater neuropathic pain intensity but also higher le...

KEY FINDING: Paralympic athletes reported significantly greater neuropathic pain intensity than recreational athletes.

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PharmacologyNeurologyPain Management

Long-range action of an HDAC inhibitor treats chronic pain in a spared nerve injury rat model

bioRxiv preprint, 2023 • December 14, 2023

The study demonstrates that a triple combination formulation (TCF) containing the HDAC inhibitor vorinostat can effectively treat chronic neuropathic pain in a spared nerve injury (SNI) rat model. A s...

KEY FINDING: A single injection of the TCF significantly reduced mechanical allodynia (pain from normally non-painful stimuli) for up to four weeks in SNI rats.

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Pain ManagementGeneticsRehabilitation

Analgesic Effect of Exercise on Neuropathic Pain via Regulating the Complement Component 3 of Reactive Astrocytes

Anesth Analg, 2024 • October 1, 2024

The study demonstrates that exercise can alleviate neuropathic pain in mice by affecting astrocytes, a type of cell in the spinal cord. Exercise reduces the activity of these astrocytes and normalizes...

KEY FINDING: Exercise training reversed mechanical and cold allodynia and improved pain-related gait behaviors in an SNI-induced neuropathic pain mice model.

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NeurologyPain ManagementGenetics

Enhancing spinal cord stimulation-induced pain inhibition by augmenting endogenous adenosine signalling after nerve injury in rats

British Journal of Anaesthesia, 2024 • February 2, 2024

This study aimed to elucidate the roles of adenosine A1 and A3 receptors (A1R, A3R) in the inhibition of spinal nociceptive transmission by SCS, and further explored whether 20-deoxycoformycin (dCF), ...

KEY FINDING: Adora1 is highly expressed in spinal neurones, including both VGlut2-labelled excitatory neurones and Pax2-labeled inhibitory interneurones, but only in a small percentage of glial cells.

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Spinal Cord InjuryNeurologyPain Management

The possible neural mechanism of neuropathic pain evoked by motor imagery in pediatric patients with complete spinal cord injury: A preliminary brain structure study based on VBM

Heliyon, 2024 • January 17, 2024

This study demonstrates that MI can evoke a below-level NP in some, but not all, pediatric CSCI patients without NP. The different results were related to individual differences in pediatric brain reo...

KEY FINDING: MI could evoke NP in some pediatric CSCI patients, but not in others.

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