Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 221-230 of 682 results
Mediators of Inflammation, 2023 • July 10, 2023
This study investigates the role of TMEM100 in NP using CCI and TNI rat models. It found that TMEM100 expression is significantly reduced in the DRG of rats with peripheral NP. AAV6-mediated delivery ...
KEY FINDING: TMEM100 expression is significantly reduced in the DRG of rats with peripheral neuropathic pain induced by tibial nerve injury (TNI) and chronic constriction injury (CCI).
Frontiers in Neurology, 2023 • July 12, 2023
This study investigated the acceptability, usability, and feasibility of the Experience Sampling Method (ESM) in patients with chronic secondary neuropathic and musculoskeletal pain syndromes. The stu...
KEY FINDING: The general evaluation showed no significant influence of ESM on participants’ social contacts, activities, or mood.
Bioengineering, 2023 • July 20, 2023
The study aimed to identify brain regions involved in maintaining a resting state and their link to neuropathic pain (NP) severity in patients with incomplete spinal cord injury (SCI). Graph theory an...
KEY FINDING: Patients with moderate to severe neuropathic pain showed reduced node degree and fALFF (fractional Amplitude of Low Frequency Fluctuation) in the left middle frontal gyrus compared to those with mild pain and healthy controls.
Frontiers in Neurology, 2023 • July 13, 2023
This study evaluated the effects of iTBS, rTMS, and iTBS+rTMS on neuropathic pain, depression, and sleep quality in individuals with SCI. Thirty-seven participants were randomly assigned to one of thr...
KEY FINDING: All three modalities (iTBS, rTMS, iTBS + rTMS) significantly improved pain, depression, and sleep quality after 4 weeks of stimulation in individuals with SCI.
Journal of Pain Research, 2023 • July 27, 2023
This study investigated the relationship between neuropathic pain (NP) and functional outcomes in spinal cord injury (SCI) patients. It aimed to determine if NP influences the degree of functional rec...
KEY FINDING: Neuropathic pain (NP) is a significant independent predictor of favorable functional outcome and higher SCIM total score at discharge.
bioRxiv, 2023 • July 28, 2023
The study aimed to determine if intraspinal microstimulation (ISMS) intended to enhance motor output after spinal cord injury (SCI) modulates spinal responsiveness to nociceptive sensory feedback. Mot...
KEY FINDING: Motor-targeted ISMS reduced nociceptive transmission across electrodes in neurologically intact animals both during and following stimulation.
Frontiers in Neurology, 2023 • August 24, 2023
This study used diffusion tensor imaging (DTI) to investigate white matter (WM) microstructural differences in patients with and without neuropathic pain (NP) after spinal cord injury (SCI). The resul...
KEY FINDING: Patients with neuropathic pain (NP) after spinal cord injury (SCI) showed significantly higher fractional anisotropy (FA) in the posterior body and splenium of the corpus callosum compared to those without NP.
Frontiers in Public Health, 2023 • July 24, 2023
The study developed and refined the SeePain, an educational resource for individuals with spinal cord injury (SCI) experiencing chronic pain, incorporating feedback from patients, their significant ot...
KEY FINDING: The SeePain resource was generally well-received by people living with SCI and their significant others, who expressed its value under a broad theme of useful and relevant information.
Pilot and Feasibility Studies, 2023 • August 3, 2023
This quasi-experimental pilot clinical trial will investigate the feasibility and potential benefits of remotely delivered Spring Forest Qigong™ for reducing neuropathic pain in adults with spinal cor...
KEY FINDING: The study will determine whether remotely delivered Qigong is feasible and well-tolerated and whether it reduces neuropathic pain in adults with SCI.
J. Clin. Med., 2023 • September 4, 2023
This study investigated the impact of immersive virtual reality walking (VRWalk) on neuropathic pain (NP) following spinal cord injury (SCI), focusing on changes in thalamic GABA content. The findings...
KEY FINDING: Participants showed a significant decrease in NRS ratings of average pain collected prior to and following the intervention.