Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 241-250 of 682 results
Int. J. Mol. Sci., 2024 • February 1, 2024
The study investigates the mechanisms behind electroacupuncture's (EA) therapeutic effects on neuropathic pain in mice with spared nerve injury (SNI). EA treatment reduced SNI-induced neuropathic pain...
KEY FINDING: Electroacupuncture (EA) at 2 Hz partially attenuated mechanical hyperalgesia and fully reduced thermal hyperalgesia in mice with spared nerve injury (SNI).
Frontiers in Immunology, 2024 • January 29, 2024
This review comprehensively describes the mechanisms underlying the inflammatory response and Treg cell regulation subsequent to spinal cord injury, with a specific focus on exploring the potential mech...
KEY FINDING: Inflammation following spinal cord injury involves the release of mediators like cytokines and chemokines, which stimulate sensory neurons and increase neuronal excitability, leading to pain perception.
Scientific Reports, 2024 • February 20, 2024
This study explores the optimal voltage for high-voltage pulsed radiofrequency (HVPRF) to treat neuropathic pain (NeP) in spared nerve injury (SNI) rats, focusing on pain reduction and underlying mech...
KEY FINDING: HVPRF application on the DRG significantly reduced mechanical allodynia, cold allodynia, and spontaneous pain induced by SNI in rats, with 85VPRF showing the best therapeutic efficacy.
Curr J Neurol, 2023 • August 14, 2023
This study assessed chronic pain and its associated factors among Lebanese individuals with spinal cord injury (SCI) to determine the impact of pain on their quality of life (QOL). The results indicat...
KEY FINDING: Chronic pain is highly prevalent (81.5%) among Lebanese individuals with SCI, with neuropathic pain being the most common type.
Cureus, 2024 • February 1, 2024
This case report highlights a rare instance of position-dependent intrathecal baclofen catheter failure, leading to debilitating spasticity and withdrawal symptoms in a young quadriplegic male. The st...
KEY FINDING: The initial catheter anchoring occurred directly adjacent to the vertebrae, leading to a position-dependent catheter occlusion.
The Journal of Spinal Cord Medicine, 2025 • February 29, 2024
This systematic review and meta-analysis aimed to determine the prevalence of opioid use among adults with SCI living in the community. The analysis included 38 studies with a total cohort size of 50,...
KEY FINDING: The pooled prevalence of opioid use among adults with SCI was 39%.
J Cell Mol Med, 2024 • January 1, 2024
This study demonstrates the remarkable efficacy of EA intervention in ameliorating pain hypersensitivities induced by CCI and protecting neurons against injury and loss in NP rats. Moreover, EA effect...
KEY FINDING: EA treatment effectively attenuated CCI-induced pain hypersensitivity and mitigated neuron damage and loss in the spinal cord of NP rats.
Frontiers in Neurology, 2024 • March 27, 2024
This study compared the effectiveness of rTMS on M1 and LDLPFC for treating neuropathic pain in spinal cord injury patients. It found both targets effective in reducing pain, anxiety, and improving sl...
KEY FINDING: Both rTMS targeting M1 and LDLPFC significantly reduced pain, anxiety, and improved sleep quality in SCI-NP patients compared to the control group.
Frontiers in Neuroscience, 2024 • May 1, 2024
The study investigates differences in EEG signals and brain network connectivity between spinal cord injury (SCI) patients with neuropathic pain (NP) and those with numbness to identify potential trea...
KEY FINDING: Patients with neuropathic pain (PWP) showed lower θ and α bands PSD values in multiple channels of regions including the frontal, premotor, motor, and temporal regions compared with the patients with numbness (PWN) group.
South African Journal of Physiotherapy, 2024 • May 6, 2024
This scoping review aimed to identify and critically appraise existing clinical practice guidelines for chronic pain management in the spinal cord injury (SCI) population. The review found that most g...
KEY FINDING: One guideline met all the objectives of this scoping review.