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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Orthopedics Research

Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.

Showing 1-10 of 452 results

OrthopedicsRehabilitationDermatology

A Multi-Systems Approach to Human Movement after ACL Reconstruction: The Integumentary System

International Journal of Sports Physical Therapy, 2022 • January 1, 2022

The integumentary system (IS) is often overlooked in ACLR rehabilitation, but impairments can limit movement. The IS contributes to temperature regulation, sensation and mobility. Assessment of the IS...

KEY FINDING: The integumentary system contributes to thermoregulation, sensation, and fascial mobility, all crucial for rehabilitation after ACLR.

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Pain ManagementGeneticsOrthopedics

MicroRNA-146a is Linked to Pain-related Pathophysiology of Osteoarthritis

Gene, 2011 • July 1, 2011

The study demonstrates that miR-146a regulates cartilage-degrading proteases and pain-associated inflammatory molecules in knee joint tissues. MiR-146a functions in an anti-catabolic manner by antagon...

KEY FINDING: MiR-146a suppresses extracellular matrix proteins in human knee chondrocytes and regulates inflammatory cytokines in human knee joint synovial cells.

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Spinal Cord InjuryNeurologyOrthopedics

Postmortem findings in a woman with history of laminoplasty for severe cervical spondylotic myelopathy

The Journal of Spinal Cord Medicine, 2011 • January 1, 2011

This case report presents the postmortem findings of a 65-year-old woman with CSM who underwent laminoplasty. The autopsy revealed significant structural changes in the spinal cord, including atrophy ...

KEY FINDING: Atrophy was observed in the ventral gray matter at the C4-C5 level, causing a triangular shape in cross-sections of the spinal cord.

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SurgeryOrthopedicsMusculoskeletal Medicine

Comparison of the long-term efficacy of ROI-C and conventional cage-plate in treatment of spinal cord injury without fracture or dislocation: a retrospective study

BMC Musculoskeletal Disorders, 2024 • October 21, 2024

This retrospective study compared the efficacy of ROI-C and conventional cage-plate (CCP) in improving cervical stability in patients with spinal cord injury without fracture or dislocation (SCIWFD). ...

KEY FINDING: Both ROI-C and CCP groups achieved bony fusion at the final follow-up, indicating similar efficacy in promoting spinal stability.

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Regenerative MedicineGeneticsOrthopedics

Regenerative medicine in orthopedics using cells, scaffold, and microRNA

J Orthop Sci, 2014 • May 13, 2014

This review focuses on regenerative medicine research using cells, scaffolds, and miRNA for clinical application in orthopedics. It highlights the importance of these components in tissue engineering ...

KEY FINDING: The use of cells combined with a cell-delivery system, miRNA, scaffold, and cytokines has led to effective regeneration of musculoskeletal tissues including cartilage, bone, ligaments, muscle, peripheral nerves, and spinal cord.

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Spinal Cord InjurySurgeryOrthopedics

Current and future surgery strategies for spinal cord injuries

World J Orthop, 2015 • January 18, 2015

Spinal cord trauma is a prominent cause of mortality and morbidity. Aim of the surgery is to decompress the spinal channel and to restore the spinal alinement and mobilize the patient as soon as possi...

KEY FINDING: Spinal compression and neurological deficit are major factors in deciding whether to perform surgery.

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Spinal Cord InjuryTraumaOrthopedics

Severe traumatic dislocation of the lower cervical spine with mild neurological symptoms: Case reports and literature review

The Journal of Spinal Cord Medicine, 2025 • July 29, 2024

This paper reports three cases of severe lower cervical dislocation without spinal cord injury and discusses the mechanisms underlying this type of injury. In all cases, the fractures occurred at the ...

KEY FINDING: Severe traumatic dislocation of the lower cervical spine with intact neurological status is rare in clinical practice.

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HealthcareOrthopedicsBiomedical

Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects: Reconstruction, anti-infection, and osseointegration

Bioactive Materials, 2024 • July 30, 2024

This study introduces a novel approach to treating infected bone defects using a 3D-printed porous Ti6Al4V implant modified with microarc oxidation (MAO) and loaded with a vancomycin-encapsulated hydr...

KEY FINDING: The vancomycin-encapsulated hydrogel, when loaded into the microarc-oxidized 3D-printed porous Ti6Al4V implant, exhibits effective antibacterial activity against MRSA both in vitro and in vivo.

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SurgeryOrthopedics

Analysis of Failed Posterior Fossa Decompression and an Effective Revision Surgery in Patients with Basilar Invagination and Atlantoaxial Dislocation

Orthopaedic Surgery, 2024 • December 1, 2024

This study analyzes the outcomes of patients with basilar invagination and atlantoaxial dislocation (BI-AAD) who underwent failed posterior fossa decompression (PFD) and introduces a novel revision su...

KEY FINDING: The revision surgery significantly improved the JOA and SF-12 scores one year after the operation, indicating better clinical symptoms and health status.

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SurgeryOrthopedicsSpinal Disorders

Effects of two posterior procedures for treatment of cervical hyperextension injury with multilevel spinal stenosis: A retrospective study

BMC Musculoskeletal Disorders, 2024 • November 19, 2024

This retrospective study compared laminoplasty with selective unilateral pedicle screw fixation and laminectomy with bilateral lateral mass screw fixation for treating cervical hyperextension injury c...

KEY FINDING: Both surgical procedures led to significant improvements in postoperative AISA scores compared to preoperative scores, indicating enhanced neurological function after surgery.

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