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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Orthopedics Research

Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.

Showing 11-20 of 452 results

SurgeryOrthopedicsSpinal Disorders

Feasibility and Safety of the C1 “Zero Angle” Screw: A Novel “In–Out–In” Technique for Atlantoaxial Dislocation

Orthopaedic Surgery, 2025 • January 1, 2025

The study introduces and evaluates the C1ZAS technique with an “in-out-in” approach as an alternative to C1 PS placement for AAD patients, especially those with narrow C1 pedicles. The radiographic an...

KEY FINDING: The C1ZAS technique, using an “in-out-in” approach, is a feasible alternative to C1 pedicle screw (PS) placement, particularly in patients with AAD and narrow C1 pedicles.

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Spinal Cord InjurySurgeryOrthopedics

Anterior Controllable Antedisplacement and Fusion (ACAF) for Cervical Stenosis Patients With Hyperextension Injury: A Retrospective Study

Orthopaedic Surgery, 2025 • January 1, 2025

This study aimed to investigate the clinical outcomes of ACAF for cervical stenosis patients with CCS due to hyperextension injury. Finally, 13 patients (7 male and 6 female) with the minimum of 12-­m...

KEY FINDING: ACAF can be a good option for treating CCS patients due to hyperextension injury with underlying cervical spondylosis and stenosis.

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OrthopedicsSpinal Disorders

Factors associated with postoperative coronal imbalance in adult patients with severe and rigid scoliosis: a retrospective study

Journal of Orthopaedic Surgery and Research, 2024 • December 1, 2024

This retrospective study analyzed 90 adult patients with severe rigid scoliosis (SRS) who underwent posterior column osteotomy (PCO) and fusion to identify risk factors for postoperative coronal imbal...

KEY FINDING: Preoperative coronal imbalance (CIB+) is significantly associated with postoperative CIB [OR = 12.414 (95% CI: 2.228, 69.162), P = 0.004].

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SurgeryOrthopedicsBiomedical

Long-Term Outcomes of Nano-Hydroxyapatite/Polyamide 66 Strut in Thoracolumbar Burst Fractures

Med Sci Monit, 2024 • December 24, 2024

Long-term results of clinical and radiographic assessment of the n-HA/PA66 strut in treating thoracolumbar burst fractures could achieve satisfactory solid anterior support, effective restoration of i...

KEY FINDING: At the final FU, the patients of ASIA B, C, and D recovered to E.

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Spinal Cord InjuryMedical ImagingOrthopedics

Impact of titanium mesh cage slotting width on anterior cervical corpectomy and fusion for compression cervical spondylosis with MRI T2WI hyperintensity: a one-year follow-up study

Journal of Orthopaedic Surgery and Research, 2024 • December 3, 2024

This study evaluated the impact of titanium mesh cage (TMC) slotting width on the outcomes of anterior cervical corpectomy and fusion (ACCF) in patients with spinal cord compression type cervical spon...

KEY FINDING: Patients in both groups showed significant postoperative improvement in NDI and JOA scores, indicating that ACCF is effective regardless of the slotting width.

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ImmunologyOrthopedicsResearch Methodology & Design

Cervical spine infection arising from chronic paronychia: A case report and review of literature

World Journal of Orthopedics, 2024 • December 18, 2024

This case report presents a unique instance of a 15-year-old male developing acute cervical spine pyogenic infection (CSPI) secondary to chronic paronychia caused by Staphylococcus aureus. The patient...

KEY FINDING: The study highlights a rare case of cervical spine pyogenic infection (CSPI) stemming from chronic paronychia, emphasizing that infections can originate from unexpected sources.

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Regenerative MedicineImmunologyOrthopedics

Additional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection

Journal of Molecular Histology, 2025 • January 6, 2025

This study evaluated the therapeutic effect of combined ceftriaxone and ADMSCs in a rodent model of acute spinal infection (ASI). The results showed that the combined therapy was superior to ceftriaxo...

KEY FINDING: The combination of ceftriaxone and ADMSCs resulted in significantly lower levels of TNF-α and IL-6 in both circulatory and spinal cord fluid compared to ceftriaxone or ADMSCs alone, indicating a stronger anti-inflammatory effect.

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OrthopedicsSpinal DisordersBioinformatics

Machine learning analysis of cervical balance in early-onset scoliosis post-growing rod surgery: a case-control study

Scientific Reports, 2025 • January 9, 2025

The study aimed to analyze cervical sagittal alignment changes following growing rod treatment in early-onset scoliosis (EOS) and identify risk factors for cervical imbalance using machine learning. T...

KEY FINDING: Growing rod surgery significantly affects cervical sagittal alignment in EOS patients.

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SurgeryOrthopedicsSpinal Disorders

Scoliosis in adult Type 1 Chiari malformation with syringomyelia patients: from pathogenesis to treatment

Am J Transl Res, 2024 • December 30, 2024

This review explores the pathogenesis and treatment of scoliosis in adult Type 1 Chiari malformation patients with syringomyelia (CIM-SM), highlighting the complexities of surgical intervention. Key a...

KEY FINDING: Adult CIM patients often have more severe clinical manifestations, including brainstem and cranial nerve compression, leading to scoliosis deformities being overlooked.

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OrthopedicsSpinal Disorders

Expression of MMP1, MMP3, and TIMP1 in intervertebral discs under simulated overload and microgravity conditions

Journal of Orthopaedic Surgery and Research, 2025 • January 16, 2025

This study investigated the impact of simulated overload and microgravity on intervertebral disc degeneration in rabbits. The researchers focused on the expression of MMP1, MMP3, and TIMP1. The study ...

KEY FINDING: MMP1 and MMP3 expression increased significantly in experimental groups compared to controls. The increase correlated with longer exposure to simulated overload and microgravity.

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