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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Orthopedics Research

Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.

Showing 21-30 of 452 results

AgingGeneticsOrthopedics

Comprehensive Analysis Reveals the Potential Diagnostic Value of Biomarkers Associated With Aging and Circadian Rhythm in Knee Osteoarthritis

Orthopaedic Surgery, 2025 • January 12, 2025

This study aimed to explore the role of aging and circadian rhythm-related genes in knee osteoarthritis (KOA). Differentially expressed genes (DEGs) were identified from the GEO database and intersect...

KEY FINDING: Identified 75 differentially expressed aging-circadian rhythm related genes between normal and KOA groups, primarily enriched in the circadian rhythm pathway.

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Medical ImagingPediatricsOrthopedics

Modified Center-Edge Angle in Children with Developmental Dysplasia of the Hip

J. Imaging, 2025 • December 27, 2024

This study introduces a modified center-edge (CE) angle to improve the diagnosis of developmental dysplasia of the hip (DDH) in young children, as the standard CE angle is unreliable in this age group...

KEY FINDING: The modified CE angle (MCE) exhibited high sensitivity and specificity, comparable to the standard CE angle, for children under and over four years old.

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SurgeryTraumaOrthopedics

Association Between Trauma-Induced Vertebral Fractures and Motor Weakness in Patients With Diffuse Idiopathic Skeletal Hyperostosis

Cureus, 2024 • December 26, 2024

Approximately half of the DISH-related spinal fractures were accompanied by neurological symptoms, and 41% of the patients exhibited paralysis. Severe spinal canal stenosis on sagittal CT and MR was i...

KEY FINDING: Approximately half of DISH-related spinal fractures were accompanied by neurological symptoms, and 41% of the patients exhibited paralysis.

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SurgeryOrthopedics

Comparison of clinical efficacy of posterior percutaneous endoscopic cervical discectomy versus unilateral biportal endoscopy key-hole techniques for cervical spondylotic radiculopathy: a retrospective study with 2 years

Journal of Orthopaedic Surgery and Research, 2025 • February 14, 2025

This retrospective study compared PECD and UBE for CSR treatment, finding both effective in improving VAS and NDI scores. The study included 70 patients, with 40 undergoing PECD and 30 undergoing UBE....

KEY FINDING: UBE group had shorter operative time compared to the PECD group (65.6 ± 17.6 vs. 85.1 ± 24.2 min, p < 0.001), but the former had longer incision length than the latter (2.4 ± 0.4 cm vs. 1.3 ± 0.4 cm, p < 0.001).

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Pain ManagementSurgeryOrthopedics

A Rare Case of Bilateral Foot Drop Following Cervical Decompression in Tandem Spinal Stenosis

Cureus, 2024 • December 29, 2024

This case report presents a rare instance of bilateral foot drop following cervical decompression in a patient with tandem spinal stenosis, complicated by white cord syndrome. The patient's postoperat...

KEY FINDING: The patient experienced transient improvements post-cervical decompression but later developed delirium, worsening right-sided weakness, and bilateral foot drop.

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Regenerative MedicineOrthopedicsBiomedical

Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing

Journal of Tissue Engineering, 2025 • January 8, 2025

This study explores the potential of umbilical cord mesenchymal stem cells (UCMSCs) in treating rotator cuff tendon injuries, which often lead to shoulder pain and dysfunction. The research identifies...

KEY FINDING: CTGF was found to be the most effective growth factor for inducing the differentiation of UCMSCs into tendon cells, leading to changes in cell morphology and increased expression of tendon-specific proteins.

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SurgeryMedical ImagingOrthopedics

Delayed Neurological Deficits Following Lumbar 1 Burst Fracture: A Diagnostic Challenge Without Radiological Correlates

Cureus, 2024 • December 31, 2024

This case report presents a diagnostic challenge involving a patient with a stable L1 burst fracture who developed delayed neurological deficits without corresponding radiological abnormalities. The p...

KEY FINDING: A 55-year-old man with a stable L1 burst fracture developed delayed neurological deficits two weeks after sustaining a fall, despite no evidence of intrinsic or extrinsic spinal cord abnormalities on MRI.

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ImmunologyOrthopedicsSpinal Disorders

Modified posterior vertebral column resection for extremely severe post-tubercular kyphosis in adults: a two-year follow-up

Journal of Orthopaedic Surgery and Research, 2025 • February 10, 2025

This study retrospectively analyzed 22 patients with severe post-tubercular kyphosis (PTK) who underwent modified posterior vertebral column resection (mPVCR). The results demonstrated significant imp...

KEY FINDING: The modified PVCR technique resulted in a significant improvement in kyphosis angle (KA) from 129.5° to 43.7° postoperatively.

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SurgeryOrthopedics

Sensitivity of intraoperative electrophysiological monitoring for scoliosis correction in identifying postoperative neurological deficits: a retrospective chart review of the Scoliosis Research Society morbidity and mortality database

BMC Musculoskeletal Disorders, 2025 • November 26, 2024

This retrospective study assessed the effectiveness of intraoperative electrophysiological monitoring in detecting postoperative neurological deficits in scoliotic patients undergoing surgical correct...

KEY FINDING: Intraoperative monitoring was used in approximately 60% of scoliosis surgeries with reported complications.

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SurgeryOrthopedics

Diagnosis and treatment of postoperative voice complications following anterior cervical discectomy and fusion: a systematic review

Journal of Orthopaedic Surgery and Research, 2025 • January 6, 2025

This systematic review consolidates research on dysphonia following ACDF, revealing inconsistencies in prevalence, clinical presentation, and measurement. The variability in reported dysphonia inciden...

KEY FINDING: The incidence of voice complications after ACDF varied widely, from 0.3 to 27%, likely due to differing measurement methods.

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