Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 131-140 of 200 results
Clinical and Molecular Hepatology, 2012 • September 1, 2012
This case report describes a 57-year-old man who developed paraplegia after undergoing TACE for costal metastasis of hepatocellular carcinoma. The patient presented with sudden sensory and motor funct...
KEY FINDING: A patient developed paraplegia following TACE targeting a costal metastasis of hepatocellular carcinoma.
Ann Rehabil Med, 2013 • April 1, 2013
This case report describes a rare instance of a giant cell tumor (GCT) in the T2 vertebra of an adolescent female, leading to spinal cord injury and subsequent neurological deficits. The patient under...
KEY FINDING: The patient presented with upper back pain and sudden weakness of the lower extremities due to a GCT on the T2 vertebra.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This case report describes a 42-year-old female with T-cell ALL who developed dorsal column myelopathy following intrathecal chemotherapy. The patient experienced ascending lower limb numbness and bal...
KEY FINDING: The patient developed ascending, symmetric circumferential numbness in both lower limbs within 24 hours of intrathecal chemotherapy.
Neural Regeneration Research, 2014 • January 1, 2014
This retrospective study evaluated the impact of early rehabilitation on neurofunctional outcomes in 70 pediatric patients who underwent spinal tumor surgery. The patients received rehabilitation trea...
KEY FINDING: Early rehabilitation significantly improved sensory function, motor function, and activity of daily living in pediatric children after spinal tumor surgery.
Photoacoustics, 2021 • July 17, 2021
This study focuses on enhancing the photostability of gold nanostars (GNSs) by coating them with silica shells for improved performance in photoacoustic imaging (PAI) and photothermal therapy (PTT). T...
KEY FINDING: Silica-coated GNSs exhibit a threefold improvement in photoacoustic stability compared to uncoated GNSs, making them more reliable for PAI.
BIOENGINEERED, 2021 • August 23, 2021
This study identifies alternative splicing events associated with bladder cancer bone metastasis and constructs a predictive model for prognosis. The research proposes a regulatory mechanism involving...
KEY FINDING: Alternative splicing events (ASEs) are associated with the occurrence and progression of bladder cancer and have a relationship with its prognosis.
ONCOLOGY LETTERS, 2021 • January 1, 2021
The present study aimed to describe the clinical characteristics, and to construct and validate nomograms for patients with non‑metastatic Ewing sarcoma. Age, sex, tumor extension and surgery were in...
KEY FINDING: Age, tumor extension, sex, International Classification of Diseases for Oncology, 3rd Edition histology, surgery and chemotherapy were identified as independent risk factors for OS and CSS.
J Immunother Cancer, 2021 • January 1, 2021
This study demonstrates the feasibility of redirecting pre-existing viral immunity against measles virus (MeV) to inhibit tumor growth in a preclinical model of aggressive squamous cell carcinoma. The...
KEY FINDING: MeV vaccination generated cytotoxic T lymphocyte (CTL) immunity in mice, demonstrated by enhanced interferon gamma production and antigen-specific T cell proliferation.
International Journal of Molecular Sciences, 2022 • January 5, 2022
The study evaluates the effectiveness of spliceosome-mediated RNA trans-splicing (SMaRT) as a targeted cancer therapy approach for epidermolysis bullosa-associated skin cancer (RDEB-SCC). The results ...
KEY FINDING: RTM44, an RNA trans-splicing molecule, can effectively target the cancer gene Ct-SLCO1B3 in RDEB-SCC cells, leading to the expression of a fusion product at the mRNA and protein level.
Cell Proliferation, 2022 • January 2, 2022
This study identifies Toll-7 as a proto-oncogene in Drosophila that promotes tumor growth and invasion. Toll-7 activates Egr-JNK and EGFR-Ras signaling pathways, leading to cell proliferation, tissue ...
KEY FINDING: Loss of Toll-7 suppresses tumor growth and invasion in a Drosophila model of RasV12/lgl−/−-induced tumors.