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  4. Primary Melanocytomas of the Spinal Cord: Case Studies and Rehabilitation Perspectives

Primary Melanocytomas of the Spinal Cord: Case Studies and Rehabilitation Perspectives

Archives of Rehabilitation Research and Clinical Translation, 2021 · DOI: https://doi.org/10.1016/j.arrct.2021.100143 · Published: January 1, 2021

OncologyNeurologyRehabilitation

Simple Explanation

Primary melanocytomas of the central nervous system are rare tumors that originate from melanocytes in the leptomeninges (membranes surrounding the brain and spinal cord). These tumors can cause symptoms such as back pain, neurological deficits, and bowel/bladder issues. Advanced imaging, like MRI, is useful for locating the tumor, but it cannot differentiate between primary melanocytomas and metastatic melanoma. This case series presents three patients with spinal cord injuries caused by malignant melanocytomas. The rehabilitation team plays a crucial role in the care of patients undergoing resection of these spinal cord tumors. Their involvement is important preoperatively, postoperatively, and during follow-up to monitor for recurrence and optimize the patient's function.

Study Duration
12-month
Participants
3 patients with nontraumatic spinal cord injuries
Evidence Level
Level 4: Case Series

Key Findings

  • 1
    Primary spinal melanocytomas, though rare, may be more common than reported due to their insidious nature and non-specific symptoms, potentially leading to delayed or missed diagnoses.
  • 2
    Postsurgical deficits after resection of spinal melanocytomas can include hemiparesis, proprioceptive impairment, spasticity, and neurogenic bowel and bladder, all of which can be addressed through intensive inpatient rehabilitation.
  • 3
    The study highlights the locally aggressive nature of spinal melanocytomas and the challenges in their treatment, emphasizing the need for a combination of surgical and radiation therapy to prevent recurrence.

Research Summary

This case series highlights the importance of the rehabilitation team in the continuum of care for patients undergoing resection of primary melanocytomas of the spinal cord. Presenting symptoms can be insidious in onset and mimic other disease states such as hydrocephalus, radiculopathy, or chronic musculoskeletal back pain. Postsurgical functional deficits can include weakness, primary sensory and proprioceptive impairments, gait instability, spasticity, and neurogenic bowel and bladder, as demonstrated by our 3 cases.

Practical Implications

Preoperative Counseling

Rehabilitation physicians should be involved in preoperative care to educate patients on potential functional changes after surgery and the role of the rehabilitation team in their postoperative care.

Acute Rehabilitation

Physiatrists are intimately involved in the acute rehabilitation of these patients during inpatient rehabilitation, addressing deficits like weakness, spasticity, and bowel/bladder dysfunction.

Follow-up and Surveillance

Rehabilitation physicians should be involved in follow-up and surveillance of recurrence of disease and addressing rehabilitative needs, including monitoring neurologic function and assessing equipment needs.

Study Limitations

  • 1
    Small sample size (3 cases)
  • 2
    Retrospective case series design
  • 3
    Lack of a unifying guideline for management of intramedullary melanocytomas

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