Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 351-360 of 5,401 results
Neural Regeneration Research, 2013 • January 1, 2013
Following spinal cord injury, numerous endogenous Schwann cells migrate into the lesion site from the nerve roots, involving in the formation of repaired tissue and myelination of regenerating and dem...
KEY FINDING: Following spinal cord injury, endogenous Schwann cells invade the lesion site, involving in tissue repair and axonal regeneration and myelination.
Neural Regeneration Research, 2013 • August 1, 2013
This study explored the mechanism of electroacupuncture at He-Mu points in treating visceral hypersensitivity in irritable bowel syndrome. The study demonstrated that electroacupuncture reduced P2X4 r...
KEY FINDING: Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) significantly reduced abdominal withdrawal reflex scores in rats with visceral hypersensitivity.
Neural Regeneration Research, 2013 • August 1, 2013
This study investigates the protective effects of basic fibroblast growth factor (bFGF) on motor endplates after spinal cord injury in rats. The distal end of the spinal cord and neuromuscular junctio...
KEY FINDING: Basic fibroblast growth factor promotes the recovery of hindlimb locomotor function in rats with spinal cord injury.
Neural Regeneration Research, 2013 • August 1, 2013
This study investigated the effect of astragaloside IV on sciatic nerve regeneration in mice, finding that it promotes repair and functional recovery. Astragaloside IV treatment resulted in increased ...
KEY FINDING: Astragaloside IV accelerates nerve myelin sheath growth in mice with sciatic nerve injury and increases the diameter and number of myelinated nerve fibers.
Neural Regeneration Research, 2013 • September 1, 2013
This retrospective study analyzed 36 cases of inflammatory demyelinating pseudotumors in the spinal cord, highlighting their clinical, imaging, and pathological characteristics to aid in differential ...
KEY FINDING: Most patients experienced acute or subacute onset, exhibiting sensorimotor disorders.
Neural Regeneration Research, 2013 • October 1, 2013
Therapeutic hypothermia is considered a promising treatment strategy for brain and spinal cord injuries, with experimental and clinical work supporting its effectiveness. The mechanisms underlying hyp...
KEY FINDING: Mild hypothermia shows promise as a novel treatment for brain and spinal cord injuries, supported by growing data.
Neural Regeneration Research, 2013 • October 1, 2013
This study evaluated the impact of olfactory ensheathing cell transplantation on sympathetic skin responses and ASIA scores in 43 patients with chronic spinal cord injury. The results showed significa...
KEY FINDING: Sympathetic skin response latency decreased significantly after olfactory ensheathing cell transplantation, indicating improved autonomic nerve function.
Neural Regen Res, 2013 • November 1, 2013
This study investigates the expression of substance P and calcitonin gene-related peptide in dorsal root ganglia of rats with sciatic nerve injury. A sciatic nerve defect model was created, and the ex...
KEY FINDING: Substance P and calcitonin gene-related peptide expression in dorsal root ganglia were altered over time in rats with sciatic nerve injury.
Neural Regen Res, 2013 • December 1, 2013
This study investigates the role of PD-L1 in the pathogenesis of experimental allergic encephalomyelitis (EAE), a mouse model for multiple sclerosis (MS). The researchers induced EAE in C57BL/6J mice ...
KEY FINDING: PD-L1 expression was significantly increased in the spinal cord of EAE mice compared to control mice, as shown by immunohistochemical staining.
Neural Regen Res, 2013 • December 1, 2013
Approximately 50–70% of patients experience incision-induced mechanical nociception after surgery. However, the mechanism underlying incision-induced mechanical nociception is still unclear. Von Frey ...
KEY FINDING: Incision surgery decreased the withdrawal threshold of rats at 0.5, 3, 6 and 24 hours after incision, compared with the sham surgery group.