Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 361-370 of 5,401 results
Neural Regen Res, 2013 • December 1, 2013
This study investigated the protective effect of curcumin on ischemic spinal cord injury in rats. Spinal cord ischemia models were created by ligating the lumbar artery, and curcumin was administered ...
KEY FINDING: Curcumin significantly improved motor function of the rat hind limb after spinal cord ischemia.
Neural Regen Res, 2013 • February 1, 2013
This study investigates the optimal time for neural progenitor cell transplantation via the subarachnoid space in rats with spinal cord injury. Cells were transplanted at acute, subacute, and chronic ...
KEY FINDING: Neural progenitor cells transplanted via the subarachnoid space can survive and improve neurological function in rats with spinal cord injuries.
Neural Regeneration Research, 2013 • February 1, 2013
This study investigates the mechanism of Erhuang capsule, a traditional Chinese medicine formula, in treating multiple sclerosis using an experimental autoimmune encephalomyelitis (EAE) mouse model. T...
KEY FINDING: Erhuang capsule reduced mortality and promoted recovery of neurological functions in mice with experimental autoimmune encephalomyelitis.
Neural Regeneration Research, 2014 • May 1, 2014
This study evaluated the combined effects of glial cell line-derived neurotrophic factor transplantation combined with adipose-derived stem cells-transdifferentiated motoneuron delivery on spinal cord...
KEY FINDING: The combined therapy of motoneuron-like cell transplantation and GDNF delivery reduced cavity formation in the injured spinal cord.
Neural Regeneration Research, 2014 • May 1, 2014
This study designed and tested a novel double-layer collagen membrane with unequal pore sizes for spinal cord injury repair. The transplantation of neural stem cells in the membrane promoted cell diff...
KEY FINDING: The double-layer collagen membrane promoted the differentiation of neural stem cells in rats with spinal cord injuries.
Neural Regeneration Research, 2014 • May 1, 2014
This study investigated whether intranasal administration of nerve growth factor (NGF) could bypass the blood-brain barrier and affect spinal cord neurons, potentially aiding in the treatment of spina...
KEY FINDING: A single intranasal administration of NGF in healthy rats increased NGF content and enhanced NGF receptor expression in the spinal cord within 24 hours.
Neural Regeneration Research, 2014 • May 1, 2014
This study investigated the analgesic effect of bumetanide, a specific sodium-potassium-chloride co-transporter 1 (NKCC1) inhibitor, and the change in spinal NKCC1 and potassium-chloride co-transporte...
KEY FINDING: Intrathecal bumetanide could decrease cumulative pain scores, and could increase thermal and mechanical pain thresholds in a rat model of incisional pain.
Neural Regeneration Research, 2014 • June 1, 2014
This study aimed to determine if long-term anode block electrical stimulation causes damage to the sacral nerve root in rabbits with complete spinal cord injury. The results indicated that the structu...
KEY FINDING: The structure of nerve cells in the anterior sacral nerve roots was unchanged in spinal cord injury rabbits after electrical stimulation, compared with normal rabbits.
Neural Regeneration Research, 2014 • June 1, 2014
This study examined the effects of miRNA-124 (miR-124) overexpression in bone marrow-derived mesenchymal stem cells, focusing on their differentiation into neurons. The researchers found that miR-124 ...
KEY FINDING: miR-124 expression is substantially reduced in bone marrow-derived mesenchymal stem cells compared with neural stem cells and neurons.
Neural Regen Res, 2014 • January 1, 2014
This study examined the effects of type-2 astrocytes on the survival and growth of dorsal root ganglion neurons in vitro. The results indicate that co-culture with type-2 astrocytes can increase neuro...
KEY FINDING: Co-culture with type-2 astrocytes increased the number of dorsal root ganglion neurons compared to culturing neurons alone.