Browse the latest research summaries in the field of neurology for spinal cord injury patients and caregivers.
Showing 341-350 of 5,401 results
Neuron, 2014 • August 20, 2014
Human iPSC-derived neural stem cells were grafted into sites of rat spinal cord injury and were found to extend axons over virtually the entire length of the rat central nervous system. These human ax...
KEY FINDING: Human iPSC-derived NSCs survived and differentiated into neurons and glia after transplantation into rats with spinal cord injuries.
Neuroreport, 2014 • October 22, 2014
The study investigated the expression of Nav1.5 in astrocytes in mouse models of multiple sclerosis (MS), specifically monophasic and chronic-relapsing experimental autoimmune encephalomyelitis (EAE)....
KEY FINDING: Nav1.5 is upregulated in astrocytes in situ in a temporal manner that correlates with disease severity in both monophasic and chronic-relapsing EAE.
PLoS ONE, 2014 • August 26, 2014
The study compared local injection of mononuclear cells (MC) to the spinal cord lateral funiculus with local delivery with fibrin sealant after ventral root avulsion (VRA) and reimplantation. Cell the...
KEY FINDING: Mononuclear cell therapy resulted in greater survival of spinal motoneurons up to four weeks post-surgery, especially when mononuclear cells were added to the fibrin glue.
PLoS ONE, 2014 • September 2, 2014
The study examined the effectiveness of electrical stimulation (ES) on nerve regeneration after delayed nerve repair in rats, with delays ranging from one day to two months. The results indicated that...
KEY FINDING: Electrical stimulation promotes nerve regeneration after delayed repair, but the effective interval is less than 1 month.
Fluids and Barriers of the CNS, 2014 • August 25, 2014
The study aimed to determine if bacterial melanin (BM) can cross the blood-brain barrier (BBB) in rats. Radioactively labeled BM was injected into rats, and its uptake in various tissues, including th...
KEY FINDING: Radioactively-labeled bacterial melanin crosses the blood–brain barrier and is enzymatically stable in blood and brain parenchyma.
Neural Regen Res, 2013 • January 1, 2013
The study investigated the distribution of GABA, tyrosine hydroxylase, and nitric oxide-producing elements in the brain of cherry salmon at different life stages using immunohistochemical and histoche...
KEY FINDING: Distribution features of nitric oxide and classical neuromediators γ-aminobutyric acid and catecholamines are closely associated with the ability of the fish brain to grow during the entire lifespan.
Neural Regen Res, 2013 • May 1, 2013
This bibliometric analysis examines the trends and characteristics of research on olfactory ensheathing cell (OEC) transplantation for spinal cord injury (SCI) over an 18-year period. The study identi...
KEY FINDING: The number of publications on OEC transplantation for SCI has shown an increasing trend over the past decade.
Neural Regeneration Research, 2013 • May 1, 2013
This study investigated the relationship between lesion positions in the brain and spinal cord and the activities of daily living in 238 multiple sclerosis patients in Shanghai, China. The results, an...
KEY FINDING: Lesions in the cerebrum, spinal cord, and supratentorial position are likely to influence activities of daily living in multiple sclerosis patients.
Neural Regeneration Research, 2013 • May 1, 2013
This study investigates the effects of gastrodin, a component of tall gastrodia tuber, on spinal cord injury recovery in rats. Gastrodin was administered to rats with induced spinal cord injuries. The...
KEY FINDING: Gastrodin treatment led to increased maximum angle in the inclined plane test and higher Basso, Beattie, and Bresnahan scores, indicating improved motor function in rats with spinal cord injuries.
Neural Regen Res, 2013 • June 1, 2013
This study investigated the effects of X-irradiation on glial scar formation and functional recovery in rats with spinal cord injury. The researchers aimed to determine the optimal time window for X-i...
KEY FINDING: X-irradiation at 8 Gy reduced the expression of macrophage marker ED-1, indicating a decrease in inflammation.