Browse the latest research summaries in the field of musculoskeletal medicine for spinal cord injury patients and caregivers.
Showing 221-230 of 278 results
Spinal Cord Series and Cases, 2019 • January 1, 2019
SCI-related osteoporosis is a common complication that leads to bone demineralization and fractures, reducing the quality of life. The loss of mechanical stimuli due to paralysis is the primary cause ...
KEY FINDING: Traumatic SCI results in various degrees of osteoporosis below the level of injury, primarily due to the loss of mechanical stimuli from paralysis.
Spinal Cord Series and Cases, 2019 • May 28, 2019
This case report describes the successful use of the “K-ing” strategy in a 16-year-old girl with a spinal cord injury and bilateral ankle fractures. The strategy allowed for early mobilization and pos...
KEY FINDING: The “K-ing” strategy (kneel standing/kneel walking) facilitated truncal activation without loading the ankle joints, which allowed for upright posture stability.
Journal of Rehabilitation and Assistive Technologies Engineering, 2019 • January 1, 2019
This study investigates the effects of different multi-electrode stimulation patterns using doublet pulses on muscle fatigue. The results demonstrate that asynchronous stimulation with doublet pulses ...
KEY FINDING: Asynchronous stimulation patterns (AsynS and AsynR) resulted in a higher normalised fatigue index compared to synchronous stimulation.
Physiol Rep, 2019 • August 5, 2019
This study examined the effects of spinal cord injury (SCI) on oxidative stress and antioxidant defenses in human skeletal muscle over the first year post-injury. Muscle biopsies were analyzed at 1, 3...
KEY FINDING: Increased protein content of NADPH oxidase 2, xanthine oxidase, and pro-caspase-3 was observed at 1 and 3 months after spinal cord injury compared to able-bodied controls, suggesting increased ROS production and apoptotic signaling.
Spinal Cord Series and Cases, 2019 • May 20, 2019
This case report describes an unusual cause of carpal tunnel syndrome in a patient with spinal cord injury: an aberrant muscle belly in the carpal tunnel compressing the median nerve. The patient, a w...
KEY FINDING: An aberrant muscle belly of the flexor digitorum superficialis of the index finger was found to be compressing the median nerve in the carpal tunnel of a patient with a spinal cord injury.
Spinal Cord Series and Cases, 2019 • July 25, 2019
This study investigated the incidence and characteristics of heterotopic ossification (HO) after spinal cord injury (SCI) in a single institution in India. It retrospectively analyzed data from 303 SC...
KEY FINDING: The incidence of heterotopic ossification (HO) in this Indian cohort of SCI patients was 6.3%.
Spinal Cord Series and Cases, 2019 • January 1, 2019
Osteoporosis and fragility fractures are prevalent and clinically meaningful in the SCI population. Prevention is a critical area of research. Although many osteoporosis medications demonstrate variab...
KEY FINDING: Bisphosphonate therapy after acute SCI may attenuate bone mineral density (BMD) loss in comparison to no treatment if administered acutely after injury.
Spinal Cord Series and Cases, 2019 • December 15, 2019
Osteoporosis is a serious complication after SCI, increasing fracture risk, but there is a lack of evidence-based guidelines for its prophylaxis and management. Current clinical practice varies widely...
KEY FINDING: There's no definitive evidence that any intervention reduces fracture risk in acute or chronic SCI due to the absence of multi-center studies adequately assessing fracture rates.
Transl Stroke Res, 2011 • December 1, 2011
This study investigates the impact of severe spinal cord injury (SCI) on the sublesional bone microenvironment in adolescent rats, focusing on the immediate effects on cellular activities at the chond...
KEY FINDING: SCI results in immediate osteocyte apoptosis in sublesional bone, followed by uncoupled bone remodeling characterized by increased osteoclast activity and decreased osteoblast activity.
Spinal Cord, 2012 • November 1, 2012
The study aimed to identify the proportion of individuals with chronic SCI that have suboptimal vitamin D status and secondary hyperparathyroidism, and to identify correlates of suboptimal vitamin D s...
KEY FINDING: Thirty-nine percent of the cohort had suboptimal serum 25(OH)D levels.