Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 41-50 of 136 results
The Journal of Spinal Cord Medicine, 2022 • January 1, 2022
This study investigates the gut microbiome composition in individuals with acute (A-SCI) and long-standing spinal cord injury (L-SCI) compared to able-bodied (AB) controls, revealing significant alter...
KEY FINDING: The gut microbiome composition differs significantly among individuals with A-SCI, L-SCI, and AB controls, as demonstrated by differences in both the alpha- and beta-diversity indices.
Scientific Reports, 2021 • June 28, 2021
This study characterized the gut microbiota in a large Italian SCI population within a short time from a traumatic injury, finding distinct dysbiotic signatures compared to healthy controls. The dysbi...
KEY FINDING: SCI patients show distinct dysbiotic signatures, including an increase in potentially pathogenic bacteria and a depletion of short-chain fatty acid producers.
BIOENGINEERED, 2021 • January 1, 2021
The study aimed to identify common gut microbiota features between patients with varying degrees of thoracic SCI and healthy individuals, and to find subpopulations of microbiota correlated with serum...
KEY FINDING: Diversity of the gut microbiota in SCI group was reduced, and with an increase in the degree of damage, alpha diversity had decreased gradually.
Scientific Reports, 2021 • August 12, 2021
This study investigated the effects of peri-arterial sympathectomy of the inferior mesenteric artery (PSIMA) on neurogenic bowel dysfunction (NBD) in spinal cord injury (SCI) rats with hyperreflexic b...
KEY FINDING: PSIMA increased the faecal water content of SCI rats by 5–13%.
EClinicalMedicine, 2021 • January 1, 2021
This multi-centre, double-blind, placebo-controlled trial assessed the efficacy of Lactobacillus casei Shirota (LcS) in preventing antibiotic-associated diarrhea (AAD) and Clostridioides difficile inf...
KEY FINDING: LcS did not significantly reduce the overall occurrence of AAD at 30 days in the entire SCI patient group (45% vs 42.1%, p = 0.639).
Spinal Cord, 2021 • October 22, 2021
The authors' study examined the utility of topical lidocaine lubricant for the amelioration of autonomic dysreflexia (AD) during bowel care in individuals living with spinal cord injury (SCI). The res...
KEY FINDING: Lidocaine did not provide any benefit in terms of severity of AD during bowel care based on all metrics of AD classification.
Microbial Biotechnology, 2022 • May 1, 2022
This study investigated the effects of electroacupuncture (EA) on gut microbial dysbiosis and the 5-HT system in spinal cord injury (SCI) rats. EA and fecal microbiota transplantation (FMT) improved i...
KEY FINDING: EA and FMT treatment facilitated intestinal transmission functional recovery and restored the colon morphology of SCI rats.
Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021
This study examined long-term bowel management trends in individuals with SCI using the NSCIMS database, revealing an initial increase in dependence at discharge followed by a shift towards greater in...
KEY FINDING: The need for total assistance with bowel management at discharge significantly increased over time (1988-2016).
Spinal Cord, 2022 • January 7, 2022
The study explores the barriers and facilitators to changing bowel care practices among individuals with spinal cord injury (SCI) using the Theoretical Domains Framework (TDF). Key findings highlight ...
KEY FINDING: Environmental context and resources, including workplace flexibility and access to support, significantly impact bowel care changes.
Top Spinal Cord Inj Rehabil, 2022 • January 1, 2022
This study examined the utility and feasibility of the International SCI/D Bowel Function Basic Data Set Version 2.0 in pediatric SCI populations. The data set was administered repeatedly to children/...
KEY FINDING: The average time to complete the data set was 5.17 minutes.