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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Endocrinology Research

Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.

Showing 101-110 of 217 results

Spinal Cord InjuryEndocrinologyRehabilitation

Early Changes in Androgen Levels in Individuals with Spinal Cord Injury: A Longitudinal SwiSCI Study

J. Clin. Med., 2022 • November 4, 2022

This study explores the longitudinal changes in androgen levels in individuals with SCI during initial rehabilitation and identifies clinical characteristics associated with these hormone levels. The ...

KEY FINDING: Total testosterone and DHEA-S levels increased significantly in men with SCI during initial rehabilitation.

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Spinal Cord InjuryEndocrinologyNutrition & Dietetics

Effects of a low-­carbohydrate/high-­protein diet on metabolic health in individuals with chronic spinal cord injury: An exploratory analysis of results from a randomized controlled trial

Physiological Reports, 2022 • November 1, 2022

This study explored the impact of an 8-week low-carbohydrate/high-protein (LC/HP) diet on metabolic health in individuals with chronic spinal cord injury (SCI). Participants were randomized to either ...

KEY FINDING: The LC/HP diet led to a significant reduction in total body fat mass and visceral fat mass compared to the control group.

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Spinal Cord InjuryEndocrinologyNutrition & Dietetics

Nutrition Education to Reduce Metabolic Dysfunction for Spinal Cord Injury: A Module-Based Nutrition Education Guide for Healthcare Providers and Consumers

J. Pers. Med., 2022 • December 7, 2022

This article reviews the existing literature on nutrition, dietary intake, and nutrition education in persons with SCI as it relates to metabolic dysfunction. Nutrition education topics are presented ...

KEY FINDING: Persons with SCI often have poor dietary intakes, not meeting recommended guidelines for fruits, vegetables, and whole grains.

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Cardiovascular ScienceEndocrinologyGenetics

Is calcium a link between inflammatory bone resorption and heart disease?

eLife, 2022 • December 29, 2022

This review explores the connection between inflammatory bone resorption and cardiovascular disease, highlighting epidemiological evidence linking conditions like osteoporosis and spinal cord injury t...

KEY FINDING: Chronic inflammatory conditions like post-menopausal osteoporosis, spinal cord injury, rheumatoid arthritis, and osteoarthritis are associated with an increased risk of cardiovascular disease.

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Spinal Cord InjuryEndocrinologyRehabilitation

Renal and Endocrine Responses to Arm Exercise in Persons with Cervical Spinal Cord Injury

J. Clin. Med., 2023 • February 20, 2023

The study assessed renal and endocrine responses to arm exercise in individuals with cervical spinal cord injury (CSCI) compared to able-bodied (AB) individuals. Key findings include that CSCI doesn't...

KEY FINDING: CSCI does not negatively impact the renal response to arm exercise, indicating that individuals with CSCI can engage in arm exercises without adverse renal effects.

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Spinal Cord InjuryEndocrinologyBrain Injury

A Systematic Review of Testosterone Therapy in Men With Spinal Cord Injury or Traumatic Brain Injury

Cureus, 2023 • January 27, 2023

This systematic review examined the effects of testosterone therapy in men with spinal cord injury (SCI) and traumatic brain injury (TBI). The review found that testosterone therapy, particularly when...

KEY FINDING: Testosterone therapy combined with exercise increased muscle size and strength in men with SCI, while testosterone alone did not show the same effect.

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EndocrinologyResearch Methodology & Design

Safety and efficacy of anti-hyperglycemic agents in patients with type 2 diabetes mellitus (T2DM): Protocol for an overview of systematic reviews based on network meta-analysis

PLOS ONE, 2023 • March 3, 2023

This study protocol describes an overview of systematic reviews based on network meta-analysis, focusing on the safety and efficacy of different anti-hyperglycemic agents for patients with T2DM. The p...

KEY FINDING: The overview aims to assess the methodological quality of published network analyses in the field of T2DM anti-hyperglycemic agents.

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Spinal Cord InjuryEndocrinology

The Physiology of Neurogenic Obesity: Lessons from Spinal Cord Injury Research

Obes Facts, 2023 • May 22, 2023

Spinal cord injury (SCI) impairs sensorimotor pathways in somatic and autonomic divisions of the nervous system, affecting multiple body systems. Obesity is the most common cardiometabolic component r...

KEY FINDING: Spinal cord injury (SCI) incites persistent metabolic derangements that have wide-ranging effects on most body systems.

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Spinal Cord InjuryEndocrinologyRehabilitation

Lean tissue mass and energy expenditure are retained in hypogonadal men with spinal cord injury after discontinuation of testosterone replacement therapy

The Journal of Spinal Cord Medicine, 2015 • January 1, 2015

This study investigated the retention of favorable changes in lean tissue mass (LTM) and resting energy expenditure (REE) after discontinuation of testosterone replacement therapy (TRT) in hypogonadal...

KEY FINDING: Significant increase in LTM was observed from baseline to TRT-12M (50.2 ± 7.4 vs. 52.9 ± 6.8 kg, P < 0.01), which persisted Post-TRT compared to BL (52.2 ± 7.8 kg, P < 0.05).

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Spinal Cord InjuryEndocrinologyMusculoskeletal Medicine

Adiponectin is associated with bone strength and fracture history in paralyzed men with spinal cord injury

Osteoporos Int, 2014 • November 1, 2014

The study explored the association between adiponectin levels and bone strength in paralyzed men with spinal cord injury, finding an inverse relationship between bone strength and circulating adiponec...

KEY FINDING: Axial stiffness and maximal load were inversely associated with circulating adiponectin levels after adjusting for injury duration and lower extremity lean mass.

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