Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.
Showing 111-120 of 217 results
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This review discusses the use of neuromuscular electrical stimulation (NMES) or functional electrical stimulation (FES) to improve body composition and metabolic profile after SCI. NMES and FES traini...
KEY FINDING: Electrical stimulation, including NMES and FES, can increase muscle size in paralyzed lower extremities after SCI.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This study aimed to evaluate the effect of omega-3 fatty acids on leptin and adiponectin concentrations in patients with spinal cord injury (SCI) through a 14-month double-blinded randomized clinical ...
KEY FINDING: Fourteen months of treatment with DHA and EPA did not influence concentrations of leptin but adiponectin level was significantly decreased (P: 0.03).
JCI Insight, 2018 • August 9, 2018
This study demonstrates that cold exposure and mirabegron treatment can induce beiging of human subcutaneous WAT. The beiging response to cold was not inhibited in obese or older subjects, suggesting ...
KEY FINDING: Repeated cold exposure upregulates UCP1 and TMEM26 protein expression in subcutaneous white adipose tissue (WAT) in both lean and obese subjects.
J Bone Miner Res, 2014 • January 1, 2014
The study examined the association between circulating adiponectin or leptin levels and BMD based on the ability to walk in chronic SCI. The findings suggest that for subjects with chronic SCI, walkin...
KEY FINDING: There was a significant inverse association between adiponectin and BMD in wheelchair users independent of body composition.
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
This randomized clinical trial evaluated the impact of a 7-month nutrition education program on lipid profiles and body weight in Iranian patients with spinal cord injury (SCI). The results indicated ...
KEY FINDING: The nutrition education program did not significantly affect total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), or high-density lipoprotein cholesterol (HDL-C) levels in patients with SCI.
The Journal of Spinal Cord Medicine, 2016 • January 1, 2016
This study examined the relationship between NAFLD and low testosterone in men with chronic SCI, a population with a high prevalence of both conditions and metabolic risk factors. The results showed a...
KEY FINDING: NAFLD was diagnosed in 49.1% of the men with chronic SCI.
PLoS ONE, 2015 • February 23, 2015
The study examined serum lipid concentrations in subjects with traumatic SCI in relation to the degree of neurological involvement and time since injury, comparing them with values from a reference sa...
KEY FINDING: Cases without preserved motor function (AIS A or B) had lower total and HDL cholesterol than the others.
The Journal of Spinal Cord Medicine, 2017 • March 1, 2017
This study investigated the neuroprotective effects of melatonin on spinal cord injury (SCI) in rats, focusing on blood vessel loss and neurological impairment. The results demonstrated that melatonin...
KEY FINDING: Melatonin treatment rescued blood vessels, as indicated by increased CD31 levels and ameliorated BSCB permeability at 7 days post-injury.
The Journal of Spinal Cord Medicine, 2017 • September 1, 2017
This retrospective study analyzed serum lipid profiles in 269 SCI patients, correlating them with disease duration, lesion level/grade, and ambulation status to assess dyslipidemia risk factors. The s...
KEY FINDING: Total cholesterol, LDL cholesterol, and triglycerides were higher than normal in 21.2%, 24.4%, and 31% of the patients, respectively.
The Journal of Spinal Cord Medicine, 2017 • July 1, 2017
The study investigated the effects of FES-LEC and ACE training on protein expression in paralyzed and non-paralyzed muscles of men with chronic SCI. Results showed that both training interventions inc...
KEY FINDING: FES-LEC training led to a 3.8-fold increase in GLUT-4 protein expression in the vastus lateralis muscle.