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  4. False lumen–dependent segmental arteries are associated with spinal cord injury in frozen elephant trunk procedure for acute type I aortic dissection

False lumen–dependent segmental arteries are associated with spinal cord injury in frozen elephant trunk procedure for acute type I aortic dissection

JTCVS Open, 2023 · DOI: https://doi.org/10.1016/j.xjon.2023.05.014 · Published: September 1, 2023

Spinal Cord InjuryCardiovascular ScienceSurgery

Simple Explanation

This study investigates the link between spinal cord injury (SCI) after aortic dissection surgery and the blood supply to the spinal cord coming from the false lumen (FL) of the dissected aorta. The researchers looked at patients who had total arch replacement and frozen elephant trunk (FET) implantation for acute type I aortic dissection. They found that if segmental arteries (SAs) at the T9-L3 levels, which supply blood to the spinal cord, were completely dependent on the FL, the risk of SCI was significantly higher after surgery.

Study Duration
2020 to 2022
Participants
146 patients with acute DeBakey type I aortic dissection
Evidence Level
Not specified

Key Findings

  • 1
    FL dependency of SAs at the T9-L3 levels was significantly associated with the development of SCI following FET implantation in AAD.
  • 2
    Patients with FL-dependent SAs had a significantly higher rate of SCI compared to those with FL-independent SAs (34.3% vs 2.7%, P<.001).
  • 3
    After adjustments, FL dependency was associated with a significantly increased risk of SCI (odds ratio, 13.1; 95% confidence interval, 4.2-41.0; P<.001).

Research Summary

This study aimed to investigate the association between false lumen (FL) dependency of segmental arteries (SAs) at T9-L3 levels and the risk of spinal cord injury (SCI) following total arch replacement and frozen elephant trunk (FET) implantation in the setting of acute DeBakey type I aortic dissection (AAD). The study found that FL dependency of SAs at the T9-L3 levels was significantly associated with the development of SCI following FET implantation in AAD. The authors suggest caution when using FET in patients with FL dependency of SAs detected on preoperative imaging and propose proactive management against SCI.

Practical Implications

Surgical Planning

Surgeons should carefully assess the FL dependency of SAs at the T9-L3 levels using preoperative imaging when planning total arch replacement and FET implantation for acute DeBakey type I AAD.

Risk Stratification

Patients with FL-dependent SAs should be considered at higher risk for postoperative SCI and may benefit from modified surgical techniques or closer monitoring.

Neuroprotection Strategies

Proactive measures such as minimizing circulatory arrest time, placing a CSFD catheter, using a shorter FET, and adopting earlier anticoagulation should be considered in patients with FL-dependent SAs.

Study Limitations

  • 1
    Single-center retrospective study
  • 2
    Limited sample size
  • 3
    Findings may not be representative of the total population

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