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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Cardiovascular Science Research

Browse the latest research summaries in the field of cardiovascular science for spinal cord injury patients and caregivers.

Showing 111-120 of 339 results

Spinal Cord InjuryCardiovascular Science

Exploring lifestyle components and associated factors in newly injured individuals with spinal cord injury

Spinal Cord, 2024 • October 8, 2024

This study describes five lifestyle components in individuals newly injured with SCI and explores the co-occurrence of these components and associated personal and clinical factors. The study found th...

KEY FINDING: A significant proportion of newly injured individuals with SCI had overweight/obesity, particularly the elderly and those with non-traumatic SCI.

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Spinal Cord InjuryCardiovascular ScienceNeurology

Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series

Neurotrauma Reports, 2024 • January 1, 2024

The study investigated the hemodynamic effects of scTS applied at different vertebral locations in individuals with chronic cervical SCI. Lumbosacral stimulation (T11/12, L1/2, S1/2) consistently elev...

KEY FINDING: Stimulation of the lumbosacral vertebrae region (L1/2, S1/2, and also including T11/12) significantly elevated BP, unlike cervical or upper thoracic stimulation.

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Cardiovascular ScienceAlternative MedicinePain Management

Electroacupuncture Relieves Neuropathic Pain via Adenosine 3 Receptor Activation in the Spinal Cord Dorsal Horn of Mice

Int. J. Mol. Sci., 2024 • September 24, 2024

The study investigates the efficacy of electroacupuncture (EA) in mitigating neuropathic pain (NPP) in mice by examining the role of adenosine A3 receptors (Adora-3) in the central nervous system. EA ...

KEY FINDING: EA upregulates Adora-3 and CD73 expression while inhibiting ADA expression in the spinal cord dorsal horn (SCDH) of mice with spared nerve injury (SNI)-induced neuropathic pain.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

A Study of Hypertension and Fitness of Individuals with Spinal Cord Injury: A Cross-Sectional Study

Healthcare, 2024 • October 23, 2024

This study investigated the relationship between blood pressure and physical fitness in adults with spinal cord injuries (SCIs) using data from Korea Paralympic Committee (KPC) fitness standard test c...

KEY FINDING: The prevalence of hypertension was 24.4% among the participants with spinal cord injuries, and this prevalence varied according to the spinal cord injury impairment level.

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Spinal Cord InjuryCardiovascular ScienceGenetics

Relationship Between the Systemic Immune-Inflammation Index and Deep Venous Thrombosis After Spinal Cord Injury: A Cross-Sectional Study

Journal of Inflammation Research, 2024 • November 6, 2024

This cross-sectional study explored the relationship between the systemic immune-inflammation index (SII) and deep venous thrombosis (DVT) in patients with spinal cord injury (SCI). The study found a ...

KEY FINDING: A positive association between SII and the risk for DVT was observed (odds ratio 1.39 [95% CI 1.03–1.87]; P=0.032), independent of confounders.

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Cardiovascular ScienceEndocrinologyNeurology

Spinal cord stimulation induces Neurotrophin‑3 to improve diabetic foot disease

Medical Molecular Morphology, 2025 • November 17, 2024

The study investigates the therapeutic effect of spinal cord stimulation (SCS) on diabetic foot disease using clinical assessments of patients and a rat model of diabetic foot injury. SCS therapy impr...

KEY FINDING: SCS therapy improved the condition of patients with diabetic ischemic foot disease, as indicated by clinical assessments.

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Cardiovascular ScienceImmunologyPublic Health

The Incidence of Myocardial Infarction after Vaccination against COVID-19: a Meta-Analysis and Systematic Review

Mædica - a Journal of Clinical Medicine, 2024 • July 13, 2024

This meta-analysis and systematic review aimed to estimate the pooled incidence of myocardial infarction (MI) after COVID-19 vaccination. The study found that the incidence of MI after COVID-19 vaccin...

KEY FINDING: The incidence of MI after COVID-19 vaccines was insignificant (0%, I2=99%, P<0.001).

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Spinal Cord InjuryCardiovascular ScienceImmunology

Blocking of Tim‐3 Ameliorates Spinal Cord Ischemia‐Reperfusion Injury Through Inhibiting Neuroinflammation and Promoting M1‐to‐M2 Phenotypic Polarization of Microglia

Immunity, Inflammation and Disease, 2024 • November 13, 2024

This study investigates the role of Tim-3 in spinal cord ischemia-reperfusion injury (SCIRI) using a rat model and in vitro experiments. The aim is to explore potential therapeutic effects of a Tim-3 ...

KEY FINDING: Tim-3 is highly expressed in spinal cord tissues of SCIRI rats. Blocking Tim-3 attenuated SCIRI-induced pathological injury, neuronal apoptosis, neuroinflammation, and microglia activation (M1 polarization).

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Cardiovascular ScienceEducation

Simulator training in focus assessed transthoracic echocardiography (FATE) for undergraduate medical students: results from the FateSim randomized controlled trial

BMC Medical Education, 2025 • December 18, 2024

This study compares the effectiveness of simulator-based ultrasound training to traditional ultrasound training with human subjects for teaching theoretical and practical skills in Focused Assessed Tr...

KEY FINDING: Both simulator- and human-based training effectively developed theoretical and practical skills in FATE.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

The Acute Effect of Hot Water Immersion on Cardiac Function in Individuals with Cervical Spinal Cord Injury

J. Clin. Med., 2024 • December 13, 2024

This study examined the impact of whole-body heat stress using head-out hot water immersion (HHWI) on cardiac function in individuals with cervical spinal cord injury (CSCI) and healthy participants. ...

KEY FINDING: In healthy participants, heat stress increased left atrial contractility, left ventricular dilatation, and left ventricular contractility.

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