Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 631-640 of 904 results
Journal of Tissue Engineering, 2024 • January 1, 2024
This study investigates the potential of adipose tissue-derived stem cell (ASC) secretome as a cell-free therapy for spinal cord injury (SCI) using Xenopus laevis and mice models. The results demonstr...
KEY FINDING: ASC secretome improves functional recovery of Xenopus laevis tadpoles after SCI, promoting significant functional recovery compared to neurobasal-treated animals.
Chinese Journal of Reparative and Reconstructive Surgery, 2024 • February 1, 2024
The study explores the use of tetramethylpyrazine-loaded electroconductive hydrogel (TGTP) for spinal cord injury (SCI) repair in rats, focusing on its potential to promote angiogenesis and neuroprote...
KEY FINDING: Rats treated with TGTP (group D) showed significantly better hindlimb motor function recovery compared to the SCI group (group B) and the SCI+electroconductive hydrogel group (group C).
Regenerative Biomaterials, 2024 • January 27, 2024
The study investigates the influence of micropatterned chitosan films on the polarization of rat skin precursor-derived Schwann cells (SKP-SCs), focusing on morphology, genic phenotype, and paracrine ...
KEY FINDING: SKP-SCs cultured on 30lm size microgroove surface showed better oriented alignment phenotype.
Science Advances, 2024 • February 28, 2024
This study investigates the capacity of skeletal muscles to act as biological amplifiers of neural information by surgically rewiring nerves with varying neural capacities to a target muscle. The resu...
KEY FINDING: Skeletal muscle can be reinnervated by a number of axons multiple times its initial physiological innervation.
Journal of Nanobiotechnology, 2024 • December 6, 2024
This is a correction article for a paper published in the Journal of Nanobiotechnology. The correction addresses an error found in Figure 2D of the original publication. The corrected figure is includ...
KEY FINDING: An error was identified in the original article's Fig. 2D regarding the colony formation of Schwann cells in the EXO-1 μg/mL group.
Materials Today Bio, 2024 • February 22, 2024
This study introduces an injectable nanocomposite hydrogel (OGPGM) composed of PGA-Mn nanoparticles, oxidized sodium alginate, and gelatin for treating osteoarthritis (OA). OGPGM exhibits excellent bi...
KEY FINDING: The nanocomposite hydrogel (OGPGM) exhibits excellent biocompatibility, effectively removes ROS from chondrocytes, and reduces inflammatory factors within the joint.
Advanced Science, 2024 • March 5, 2024
This study introduces an IGF-1 bioactive supramolecular nanofiber hydrogel (IGF-1 gel) that can activate IGF-1 downstream signaling, prevent the apoptosis of neural stem cells (NSCs), improve their pro...
KEY FINDING: IGF-1 gel promotes NSC survival, proliferation, and differentiation into neurons and oligodendrocytes.
Nanomaterials, 2024 • February 20, 2024
This study successfully synthesized a curcumin-decorated nanozyme (PMC NPs) with significant ROS scavenging and anti-inflammatory properties for neuroprotection. In vitro experiments demonstrated that...
KEY FINDING: PMC NPs exhibit specific SOD-like and CAT-like activities, enabling them to effectively scavenge ROS in physiological conditions.
Journal of Nanobiotechnology, 2024 • February 29, 2024
Neurotrauma, including TBI and SCI, remains a significant global health issue with limited effective treatments. Exosomes, particularly those from non-stem cell sources, are emerging as promising ther...
KEY FINDING: Exosomes from neurons can reduce the activation of microglia and astrocytes, and promote the maturation of oligodendrocyte progenitor cells.
Journal of Biomedical Optics, 2024 • March 19, 2024
This paper introduces the photoacoustic differential attenuation spectrum (PA-DAS) method to study the attenuation characteristics of cancellous bone for osteoporosis diagnosis. The method modifies Bi...
KEY FINDING: The photoacoustic differential attenuation spectrum (PA-DAS) method can effectively differentiate osteoporotic bone from healthy bone.