Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 591-600 of 904 results
Journal of Materials Science: Materials in Medicine, 2023 • May 16, 2023
This document is an author correction to a previously published article. The corrections involve author affiliations, names, and contact information. The original article has been updated with these c...
KEY FINDING: The original article contained mistakes regarding author affiliations and names.
Biomedicines, 2023 • May 12, 2023
This study explores the therapeutic efficacy of heparin-based hydrogel micropatches containing human adipose-derived stem cells (hASCs) in treating neuropathic pain caused by nerve damage. Our results...
KEY FINDING: hASCs combined with heparin-based hydrogel micropatches enhanced nerve regeneration in a neuropathic pain animal model.
Oxidative Medicine and Cellular Longevity, 2023 • May 25, 2023
This review highlights the ability of C-dots to function as anti-inflammatory agents targeting inflammation-associated diseases, demonstrating their exceptional potential as nanomedicines. C-dots have...
KEY FINDING: C-dots exhibit anti-inflammatory effects in models of LPS-induced inflammation, gout, spinal cord injury, wound healing, and other diseases.
International Journal of Bioprinting, 2023 • February 22, 2023
This study fabricated microfiber-reinforced spinal cord ECM hydrogel-based scaffolds loaded with OMT using 3D printing, verifying their biocompatibility, degradability, and mechanical properties in vi...
KEY FINDING: The composite scaffolds loaded with OMT promoted the differentiation of NSCs into neurons and inhibited differentiation into astrocytes, suggesting a favorable environment for nerve regeneration.
Journal of Nanobiotechnology, 2023 • January 1, 2023
This is a correction article for the original article which studies Acidic and hypoxic tumor microenvironment regulation by CaO(2)-loaded polydopamine nanoparticles. The correction addresses an error ...
KEY FINDING: The authors identified an error in affiliation in the original article.
Journal of Tissue Engineering, 2023 • June 1, 2023
This study introduces a novel therapeutic approach for spinal cord injury (SCI) using black phosphorus quantum dots (BPQDs) encapsulated within Epigallocatechin-3-gallate (EGCG) hydrogels (E@BP). E@BP...
KEY FINDING: E@BP treatment enhances the structural and functional integrity of spinal cord tracts, leading to improved motor neuron function in SCI rats.
Regenerative Therapy, 2023 • May 28, 2023
This study introduces a novel Col-PPy-Qur composite for spinal cord injury (SCI) regeneration. The composite combines collagen, polypyrrole, and quercetin to mimic the spinal cord's properties and pro...
KEY FINDING: The Col-PPy-Qur composite exhibits electrical conductivity (0.0653 s/cm) and mechanical strength (0.1281 mPa) similar to the native human spinal cord.
Science Advances, 2023 • June 23, 2023
This study reports a hybrid hydrogel made from a small functional self-assembling peptide (F-SAP) and large silk fibroin (SF) for treating spinal cord injury (SCI). The F-SAP/SF hybrid hydrogel couple...
KEY FINDING: The F-SAP/SF hybrid hydrogel coupled with controlled release of NT-3 provided a permissive environment for neural regeneration.
Int. J. Mol. Sci., 2023 • June 16, 2023
This study introduces a novel OPF hydrogel scaffold with ridges and a TiSAMP surface, designed to promote nerve regeneration after spinal cord injury. The in vitro results show the scaffold supports c...
KEY FINDING: OPF sheets with ridges and TiSAMP chemical patterns promote alignment and outgrowth of cells, and also influence the directionality of the produced ECM, which could aid in nerve regeneration.
Molecules, 2023 • June 7, 2023
This review explores the role of ECM adhesion motifs in functionalized hydrogels for tissue engineering. It emphasizes the importance of mimicking the native ECM to enhance biocompatibility and stem c...
KEY FINDING: RGD motifs enhance cell viability and proliferation in hydrogels, making them suitable for articular cartilage regeneration.