Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 261-270 of 904 results
Exp Neurol, 2021 • January 1, 2021
This study presents a micro-LED (μLED) implant designed for long-term optogenetic stimulation of the rat spinal cord, emphasizing its simplicity in fabrication, implantation, and operation. The resear...
KEY FINDING: The μLED implant can provide up to 50 mW/mm2 of light for optogenetic spinal stimulation.
J NeuroEngineering Rehabil, 2020 • September 24, 2020
This study investigated the safety and feasibility of using the Myosuit, a wearable robot, to assist individuals with diverse gait disorders during activity-based training. The study found that traini...
KEY FINDING: Activity-based training with the Myosuit appears to be safe, feasible, and well-tolerated by individuals with diverse motor disorders.
Med Eng Phys, 2020 • December 1, 2020
The study designed and deployed a real-time self-righting feedback controller for restoration of trunk posture in the coronal and diagonal planes in individuals with various levels of SCI using FNS of...
KEY FINDING: The control system successfully restored upright sitting from forward, lateral or diagonal leaning without a chest strap.
J NeuroEngineering Rehabil, 2020 • November 1, 2020
This study introduces spatial filtering methods using PCA, NMF, and their combination to enhance HD-sEMG for examining neuromuscular changes, particularly in SCI patients. The experimental results sho...
KEY FINDING: The CI analysis of conventional single-channel sEMG can reveal complex neuromuscular changes in paralyzed muscles following SCI, and its diagnostic power has been confirmed to be characterized by the variance of Z scores.
Sensors, 2020 • December 16, 2020
This paper introduces a gait planning algorithm for lower limb exoskeletons that uses crutches, focusing on balance control based on the combined Center of Pressure (CoP). The algorithm determines the...
KEY FINDING: The gait planning algorithm effectively processes sensory information to determine suitable landing points for balanced walking.
ACS Biomater Sci Eng., 2019 • December 9, 2019
This study investigated regeneration using a poly(lactide-co-glycolide) (PLG) multi-channel bridge implanted into a chronic SCI following surgical resection of necrotic tissue. These data demonstrate ...
KEY FINDING: PLG bridges implanted into chronic SCI promote axonal regeneration into the injury site.
J NeuroEngineering Rehabil, 2021 • January 11, 2021
The study investigated the influence of different electrode configurations and distributed stimulation on fatigue resistance in paralyzed quadriceps muscles during dynamic knee-extension. Fatigue-test...
KEY FINDING: No significant difference in fatigue resistance was found between conventional stimulation and distributed stimulation using different electrode configurations.
Frontiers in Robotics and AI, 2020 • September 8, 2020
This study introduces and evaluates a novel control approach for lower extremity rehabilitation exoskeletons that allows users to control their gait in real-time using hand movements and sensory feedb...
KEY FINDING: The admittance-control-based system allows users to control foot trajectories with hand-generated forces and sensed foot kinematics in real-time.
J NeuroEngineering Rehabil, 2021 • January 12, 2021
This paper reviewed the design and clinical evaluation of wearable lower-limb exoskeletons intended to support walking in people with neuromuscular impairments. Wearable exoskeletons are still heavy a...
KEY FINDING: Wearable exoskeletons are heavy and bulky devices that generally require supervision and walking aids, hindering mobility and independence.
RSC Advances, 2020 • January 20, 2020
This study introduces a novel composite scaffold made of PCL and PEG, loaded with FGF2, EGF, and GDNF, designed to promote spinal cord injury (SCI) repair. The scaffold was implanted into rats with tr...
KEY FINDING: The composite scaffold, PCL/PEG/FGF2/EGF/GDNF, improved locomotor function in rats with SCI 8 weeks post-implantation.