Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 271-280 of 904 results
IEEE Trans Biomed Circuits Syst., 2021 • April 1, 2021
This paper presents the design, testing, and validation of stimulation (PG4) and biopotential recording (BP2) modules for a fully implanted modular neuroprosthesis system called the Networked Neuropro...
KEY FINDING: System testing demonstrated that the NNP was functional and capable of generating stimulus pulses and recording myoelectric, temperature, and accelerometer signals.
PNAS, 2022 • August 8, 2022
The study introduces a novel bioelectronic platform incorporating silicon carbide (SiC) nanomembranes and silicon dioxide (SiO2) biobarriers for long-term bioimplanted applications, fabricated using M...
KEY FINDING: The SiC/SiO2 bioelectronic system exhibits excellent stability and can potentially last for several decades with well-maintained electronic properties in biofluid environments.
Sensors, 2021 • April 13, 2021
This article presents a systematic review of wearable sensors and techniques used in real-time gait analysis, and their application to pathological gait. We found that heel strike and toe off are the ...
KEY FINDING: Heel strike and toe off are the most widely identified gait events, irrespective of the type of sensor used.
Frontiers in Robotics and AI, 2021 • April 27, 2021
This study presents a hybrid gait restoration system for individuals with SCI, combining implanted neural stimulation and a powered exoskeleton. The system uses a muscle-first approach, where the exos...
KEY FINDING: The addition of torque burst assistance from the exoskeleton resulted in an increase in gait speed for both SCI participants compared to passive or friction compensation modes.
Annu Int Conf IEEE Eng Med Biol Soc, 2021 • November 1, 2021
The study investigated the effects of varying pulse width and frequency of electrical stimulation on hindlimb movements in rats using a wireless floating microelectrode array (WFMA) implanted in the s...
KEY FINDING: Changing the frequency of stimulation between 1 and 50 Hz did not significantly alter the minimum current required to elicit movement in the rat hindlimb.
Sensors, 2022 • November 1, 2022
This study assessed gait capacity and gait performance in rehabilitation inpatients with stroke or iSCI using IMUs. The IMU-based gait algorithm was found to be valid for gait assessment and gait capa...
KEY FINDING: IMUs can accurately measure walking ability in patients with neurological disorders.
Sensors, 2022 • November 24, 2022
This study introduces a novel controller based on a Reinforcement Learning (RL) algorithm for real-time adaptation of the stimulation pattern during FES-cycling. The participant was able to pedal over...
KEY FINDING: The participant with spinal cord injury was able to pedal overground for distances over 3.5 km using the developed system.
Int. J. Mol. Sci., 2023 • January 3, 2023
Spinal cord injury (SCI) leads to reduced motor, sensory, and autonomic functions, with an increasing incidence worldwide. Regenerative biomaterials offer a promising treatment option by using tissue ...
KEY FINDING: Hyaluronic acid (HA) reduces glial scar formation and improves the therapeutic effect of SCI by transporting drugs and stem cells to the injury area, enhancing the survival and differentiation of neural stem cells.
Sensors, 2023 • February 1, 2023
This study developed a machine-learning-based methodology to estimate shoulder load in wheelchair-related activities using wearable sensors. The approach involved collecting data from participants per...
KEY FINDING: A subject-specific biLSTM model trained on a sparse sensor setup (upper arm IMU, WC IMUs, and EMG) yielded the most promising results, with a mean correlation coefficient of 0.74 ± 0.14 and a relative root-mean-squared error of 8.93% ± 2.49%.
Biomimetics, 2023 • February 15, 2023
This study presents a soft robotic glove designed for hand rehabilitation in virtual reality (VR). The glove uses fifteen inertial measurement units (IMUs) for finger motion tracking and a motor-tendo...
KEY FINDING: Fifteen IMUs are used for finger motion tracking, and their data is processed using a static threshold correction method and complementary filter to calculate finger attitude angles.