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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Biomedical Research

Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.

Showing 251-260 of 904 results

Spinal Cord InjuryRehabilitationBiomedical

Selective neural electrical stimulation restores hand and forearm movements in individuals with complete tetraplegia

Journal of NeuroEngineering and Rehabilitation, 2020 • April 1, 2020

The study investigated selective neural electrical stimulation of radial and median nerves to restore hand function in individuals with complete tetraplegia. The results demonstrated that selective st...

KEY FINDING: Selective stimulation using multicontact cuff electrodes can provide isolated, compound, functional, and strong movements in individuals with tetraplegia.

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NeurologyRehabilitationBiomedical

Human Gait Control Using Functional Electrical Stimulation Based on Controlling the Shank Dynamics

Basic and Clinical Neuroscience, 2020 • January 1, 2020

Efficient gait control using Functional Electrical Stimulation (FES) is an open research problem. In this research, a new intermittent controller has been designed to control the human shank movement ...

KEY FINDING: The gait process was controlled with acceptable quality, while no desired trajectories were envisioned for joint movements.

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Spinal Cord InjuryNeurologyBiomedical

Ultrasound-driven piezoelectric current activates spinal cord neurocircuits and restores locomotion in rats with spinal cord injury

Bioelectronic Medicine, 2020 • April 16, 2020

The study investigates the efficacy of piezoelectric stimulation (pES) to activate spinal cord neurocircuits compared to conventional epidural electrical stimulation (ES) in rats with spinal cord inju...

KEY FINDING: Ultrasound intensity as low as 0.1 mW/cm2 could induce MEPs in the hindlimbs of rats.

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Assistive TechnologyBiomedical

Improved Active Disturbance Rejection Control for Trajectory Tracking Control of Lower Limb Robotic Rehabilitation Exoskeleton

Sensors, 2020 • June 30, 2020

This paper introduces improved active disturbance rejection control (I-ADRC) controllers as a combination of linear extended state observer (LESO), tracking differentiator (TD), and nonlinear state er...

KEY FINDING: The proposed controllers show reduced trajectory tracking error.

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Spinal Cord InjuryRehabilitationBiomedical

Chronic nerve health following implantation of femoral nerve cuff electrodes

Journal of NeuroEngineering and Rehabilitation, 2020 • July 6, 2020

This study evaluated the clinical electrodiagnostic changes due to electrode implantation acutely, chronic presence on the nerve peri- and post-operatively, and long-term delivery of electrical stimul...

KEY FINDING: Femoral compound motor unit action potentials increased 31% in amplitude and 34% in area over 1 year of rehabilitation.

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NeurologyBiomedical

Sensory restoration by epidural stimulation of the lateral spinal cord in upper-limb amputees

eLife, 2020 • July 21, 2020

The study demonstrates the potential of epidural SCS as a method for restoring sensation in individuals with upper-limb amputations, with sensations localized to the missing limb. The evoked sensation...

KEY FINDING: Epidural spinal cord stimulation (SCS) evoked somatosensory percepts that were perceived as emanating from the missing arm and hand.

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RehabilitationBiomedicalBiomechanics

Mediolateral damping of an overhead body weight support system assists stability during treadmill walking

Journal of NeuroEngineering and Rehabilitation, 2020 • July 28, 2020

The study investigated the effect of mediolateral (ML) damping in a 3-DoF body weight support (BWS) system on walking stability in able-bodied individuals during treadmill walking. Results indicated t...

KEY FINDING: Body weight support, in general, leads to gait alterations such as increased step length and swing phase.

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NeurologyRehabilitationBiomedical

Prospects for intelligent rehabilitation techniques to treat motor dysfunction

Neural Regen Res, 2021 • February 1, 2021

Motor dysfunction from neurological diseases creates significant burdens. Rehabilitation aims to restore function, but deficits often persist, necessitating new approaches. Intelligent rehabilitation,...

KEY FINDING: Emerging intelligent rehabilitation techniques provide objective and accurate functional assessment for stroke patients.

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Spinal Cord InjuryGeneticsBiomedical

pH/Temperature Responsive Curcumin-Loaded Micelle Nanoparticles Promote Functional Repair after Spinal Cord Injury in Rats via Modulation of Inflammation

Tissue Eng Regen Med, 2023 • August 14, 2023

This study investigates the use of curcumin-loaded micelle nanoparticles (Cur-NPs) to enhance nerve regeneration and functional recovery after spinal cord injury (SCI) in rats by modulating the inflam...

KEY FINDING: Cur-NPs exhibit pH/temperature dual-sensitivity, enabling smart responsive release of curcumin in the inflammatory microenvironment after SCI, thus improving curcumin bioavailability.

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Assistive TechnologyRehabilitationBiomedical

Sensor Fusion in Assistive and Rehabilitation Robotics

Sensors, 2020 • September 14, 2020

This editorial introduces a special issue on sensor fusion in assistive and rehabilitation robotics, highlighting the increasing need for such technologies due to the aging population and the prevalen...

KEY FINDING: Wheelchair robot with leg exoskeletons and sensor fusion shows promise for leg muscle exercise.

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