Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.
Showing 241-250 of 904 results
Journal of NeuroEngineering and Rehabilitation, 2019 • December 11, 2019
The study investigated the effects of body weight support (BWS) on stair negotiation in able-bodied individuals, examining spatio-temporal parameters, joint kinematics, ground reaction forces, and myo...
KEY FINDING: Unloading affected walking velocity, joint ranges of motion, vertical ground reaction force parameters and myoelectric activity in all investigated muscles for stair ascent and descent.
Journal of Orthopaedic Translation, 2020 • January 1, 2020
The review discusses the biomechanics of the human hip joint, pathological gait, and common design approaches for robotic hip exoskeletons. It highlights the limitations of existing exoskeletons, incl...
KEY FINDING: Robotic hip exoskeletons show promise in gait rehabilitation by assisting individuals with hip disabilities through controllable assistance at the hip joints.
International Journal of Environmental Research and Public Health, 2020 • January 24, 2020
The paper introduces a concept for using big data analytics and sensor-enhanced activity management (SEAM) to improve outpatient medical rehabilitation. The proposed system aims to collect and analyze...
KEY FINDING: The project proposes a sensor-enhanced activity management (SEAM) approach, enabled by big data analytics (BDA), to improve outpatient rehabilitation effectiveness and efficiency for patients with neurological impairments.
TISSUE ENGINEERING: Part A, 2020 • February 27, 2020
The study investigates the use of polycistronic vectors to co-express IL-10 and NT-3 from a PLG bridge to enhance spinal cord regeneration after injury. The combined delivery of IL-10 and NT-3 resulte...
KEY FINDING: Combined delivery of IL-10 and NT-3 significantly increased axonal density and myelinated axons compared to other conditions.
Journal of NeuroEngineering and Rehabilitation, 2020 • March 9, 2020
This review examines FES systems for foot drop, focusing on control architecture and clinical effectiveness across common affected pathologies. It covers systems developed over the last two decades. T...
KEY FINDING: Systems capable of self-adjustment and closed-loop control are crucial for modulating assistance in individual conditions to adequately assist the patient.
Sci. Adv., 2020 • April 1, 2020
This study introduces SHIELD, an injectable hydrogel designed to improve the survival and therapeutic function of transplanted Schwann cells for spinal cord injury treatment. SHIELD addresses key chal...
KEY FINDING: SHIELD hydrogels provide protection from membrane damage during syringe needle injection, improving cell survival during transplantation.
Journal of NeuroEngineering and Rehabilitation, 2020 • March 18, 2020
The study introduces a novel Task-Adjustable Passive Orthosis (TAPO) for tremor suppression, featuring a lightweight, textile-based design with an integrated air-structure. The orthosis is manually ad...
KEY FINDING: The developed orthosis has a lightweight design (33 g) with emphasis on comfort and wearability.
Journal of NeuroEngineering and Rehabilitation, 2020 • April 1, 2020
This study investigates the use of sum of phase-shifted sinusoids (SOPS) stimulation with real-time feedback control to improve muscle output and reduce fatigue in a participant with spinal cord injur...
KEY FINDING: Open and closed-loop SOPS stimulation prolonged time to fatigue (TF) and increased total work (W) compared to constant stimulation.
Sensors, 2020 • May 12, 2020
This study evaluated the feasibility of a sensor-based technological platform for monitoring gait and sleep in iSCI and stroke patients within a clinical setting. The platform uses IMUs and a bed sens...
KEY FINDING: The percentage of missing measurement days and nights was 14% and 4%, respectively, indicating generally good data collection.
ACS Omega, 2020 • April 27, 2020
This study investigates the effectiveness of a physically cross-linked PNIPAAm-g-PEG hydrogel, injected one week post-injury, in improving functional recovery after a T10 spinal cord contusion in rats...
KEY FINDING: The hydrogel did not induce an additional inflammatory reaction at the lesion site.