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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Biomedical Research

Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.

Showing 201-210 of 904 results

NeurologyRehabilitationBiomedical

Properties of the surface electromyogram following traumatic spinal cord injury: a scoping review

J NeuroEngineering Rehabil, 2021 • January 1, 2021

This scoping review aims to summarize and critically appraise the existing literature on how SCI can alter the sEMG properties. We distilled the large SCI literature reporting sEMG properties during r...

KEY FINDING: Early reports were mostly focused on the qualitative analysis of sEMG patterns and evolved to semi-quantitative scores and a more detailed amplitude-based quantification.

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Biomedical

A Novel Framework for Quantifying Accuracy and Precision of Event Detection Algorithms in FES-Cycling

Sensors, 2021 • July 3, 2021

This study introduces a framework for evaluating the accuracy and precision of event detection algorithms used in FES-cycling. Three algorithms (Hilbert, BSgonio, and GCI Observer) were tested using i...

KEY FINDING: The Hilbert and BSgonio algorithms met the set accuracy criteria, showing good agreement with the baseline reference. BSgonio proved an accurate and precise way of detecting events reliably in real time.

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NeurologyBiomedical

Neural stimulation and recording performance in human sensorimotor cortex over 1500 days

J Neural Eng., 2021 • August 13, 2021

This study evaluated the long-term stability of intracortical microstimulation (ICMS) and neural recording in a human participant over 1500 days, comparing stimulated SIROF electrodes in somatosensory...

KEY FINDING: Recording quality decreased over time on both stimulated SIROF and non-stimulated platinum electrodes, but stimulated SIROF electrodes were more likely to continue recording high-amplitude signals.

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Spinal Cord InjuryBiomedical

Conductive and injectable hyaluronic acid/gelatin/gold nanorod hydrogels for enhanced surgical translation and bioprinting

J Biomed Mater Res A, 2022 • February 1, 2022

This study successfully developed a conductive hydrogel composed of hyaluronic acid, gelatin, and citrate-capped gold nanorods (GNRs) for potential use in spinal cord injury (SCI) treatment. The hydro...

KEY FINDING: The developed hydrogel is conductive, with conductivity increasing with GNR content up to 0.8 mg/ml.

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Assistive TechnologyBiomedical

Community-based wheelchair caster failures call for improvements in quality and increased frequency of preventative maintenance

Spinal Cord, 2022 • August 19, 2021

This study analyzed wheelchair caster failures and service repairs to determine their frequency across manufacturers and models. The results indicated that failure types were significantly associated ...

KEY FINDING: Users of tilt-in-space wheelchairs experienced twice the proportion of high-risk caster failures than the ultralightweight manual wheelchair users.

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Biomedical

Design of an FPGA-Based Fuzzy Feedback Controller for Closed-Loop FES in Knee Joint Model

Micromachines, 2021 • August 16, 2021

The paper presents the design and implementation of an FPGA-based fuzzy feedback controller (FFC) for closed-loop functional electrical stimulation (FES) in a knee joint model, aiming to reduce early ...

KEY FINDING: The digital FFC utilizes only 4% of the total FPGA (Cyclone IV E) logic elements (LEs).

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Regenerative MedicineNeurologyBiomedical

Thermosensitive collagen/fibrinogen gels loaded with decorin suppress lesion site cavitation and promote functional recovery after spinal cord injury

Scientific Reports, 2021 • September 16, 2021

This study introduces a thermosensitive injectable gel loaded with Decorin for treating spinal cord injuries in rats. The gel facilitates sustained Decorin release, reduces cavitation, promotes ECM de...

KEY FINDING: The BC/FB gel formed within 1 minute at 37 °C and released Decorin in a sustained manner for up to 30 days in vitro.

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NeurologyRehabilitationBiomedical

EEG Monitoring Is Feasible and Reliable during Simultaneous Transcutaneous Electrical Spinal Cord Stimulation

Sensors, 2021 • October 2, 2021

This study investigates the feasibility of EEG monitoring during transcutaneous electrical spinal cord stimulation (tSCS) by characterizing artifacts and evaluating artifact-suppression techniques. Th...

KEY FINDING: tSCS manifested as narrow, high-amplitude peaks in the time domain at a rate equal to the stimulation frequency, making the EEG nearly an order of magnitude more powerful than normal EEG.

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Assistive TechnologyBiomedical

A Compact and Lightweight Rehabilitative Exoskeleton to Restore Grasping Functions for People with Hand Paralysis

Sensors, 2021 • October 18, 2021

This study presents a compact and lightweight hand exoskeleton designed to aid individuals with hand paralysis in regaining grasping functions. The device utilizes a three-layered sliding spring mecha...

KEY FINDING: The developed exoskeleton can produce a fingertip force of up to 8 N and cover 91.5 degrees of range of motion in just 3 seconds.

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Assistive TechnologyBiomedicalBiomechanics

Comparison of Manual Wheelchair and Pushrim-Activated Power-Assisted Wheelchair Propulsion Characteristics during Common Over-Ground Maneuvers

Sensors, 2021 • October 22, 2021

The study compares manual wheelchair (MWC) and pushrim-activated power-assisted wheelchair (PAPAW) propulsion during common over-ground maneuvers. Findings indicate that PAPAWs reduce propulsion effor...

KEY FINDING: Using PAPAWs significantly reduces propulsion effort (RMS torque) and push frequency compared to manual wheelchairs.

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