Biomedical Research

KEY FINDING: Immobilization of cABC I on GO resulted in a greater Km and lower Vmax compared to the free enzyme.

KEY FINDING: Changes in lipid and amide I–II spectral regions are modulated by the type and coating of the substrate used and the culture time.

KEY FINDING: LDLK3 monomers and AQP4 cause different structural perturbations in the neural membrane that may be interpreted as different lipid fingerprints.

KEY FINDING: Dental stem cells are found in primary and permanent teeth, including wisdom teeth, making them a readily available resource.

KEY FINDING: FeN4O2-SACs exhibit multiple enzyme-mimicking activities, analogous to natural antioxidant enzymes, demonstrating broad-spectrum ROS scavenging capability.

KEY FINDING: G-CuNCs can assist in the fast formation of R-CuNCs, retaining their tiny size and water solubility.

KEY FINDING: Ce3+ ions can be used to crosslink and rearrange L-cysteine-protected copper nanoclusters into ordered mesoporous spheres.

KEY FINDING: MCPP-M-gel demonstrated favorable physico-mechanical properties and extended MC release over 72 hours in vitro without cytotoxic effects on neural crest-derived ectoderm mesenchymal stem cells (EMSCs).

KEY FINDING: The RISES system demonstrated safety and feasibility for tSCS application in clinical settings. There were no serious adverse events and skin integrity was unaffected at stimulation sites.

KEY FINDING: The "combo" therapy reduced M1 microglia activation and glutamate levels in the short term, indicating a strong anti-inflammatory effect.