Biomedical Research

KEY FINDING: Biomimetic membrane materials can give NPs for drug delivery the privilege of “not being eaten” in vivo and can easily pass through the BBB.

KEY FINDING: Optical coherence tomography (OCT) offers high-resolution, cross-sectional images of inhomogeneous structures like soft biological tissues on a microscopic level, as well as in 3-D.

KEY FINDING: Nanovibration intervention did not reverse SCI-induced osteoporosis in rats.

KEY FINDING: Alginate implants significantly reduced injury-induced demyelination of the contralateral white matter in the chronic state after SCI.

KEY FINDING: Following SCI in rats, complex and outer-arm fucosylated glycans decreased, while oligomannose and hybrid structures increased.

KEY FINDING: EV purity may not always correlate with functionality, and co-isolates could contribute to function and stability.

KEY FINDING: Extrusion technology generates nanosized vesicles in far greater numbers than naturally obtained EVs.

KEY FINDING: Coherent Raman scattering and third harmonic generation enable label-free visualization of myelin sheaths. Combining these with two-photon excited autofluorescence and second harmonic generation allows comprehensive tissue visualization.

KEY FINDING: Grafted HNK-1 encouraged motor neuron outgrowth, but not sensory neuron outgrowth, maintaining modality-specific responses.

KEY FINDING: Certain types of tumor have their own unique microbial composition, which has an important role in the survival of cancer patients.