Browse the latest research summaries in the field of anesthesiology for spinal cord injury patients and caregivers.
Showing 31-40 of 46 results
Neural Regeneration Research, 2015 • August 1, 2015
This study aimed to validate neuroprotective effects of combined therapy (propofol and bone marrow mesenchymal stem cells (BMSCs)) on rat spinal cord injury. Results indicate that propofol can enhance...
KEY FINDING: Combined propofol and BMSC transplantation significantly improved hindlimb motor function in rats with spinal cord injury compared to monotherapy.
Eur J Pain, 2015 • May 1, 2015
This study investigates the differential contributions of N-, L-, and P/Q-type voltage-gated calcium channels (VGCC) to behavioral hypersensitivity mediated by Cavα2δ1 dysregulation using a Cavα2δ1 ov...
KEY FINDING: N-type and L-type VGCC blockers (ω-conotoxin GVIA and nifedipine, respectively) significantly attenuated mechanical hypersensitivity in both the Cavα2δ1 overexpression (TG) and spinal nerve ligation (SNL) models.
BMC Anesthesiology, 2015 • May 29, 2015
This study evaluated the analgesic effect of immediate pulsed radiofrequency (PRF) treatment after nerve injury in a rat model of spared nerve injury (SNI). The results showed that immediate PRF appli...
KEY FINDING: Immediate PRF treatment after SNI significantly reduced mechanical and cold allodynia in rats over 28 days.
The Journal of Physiological Sciences, 2019 • March 29, 2018
The study examined the effects of isoflurane anesthesia on spinal cord neurovascular coupling in decerebrated rats during sciatic nerve stimulation. Results indicated that isoflurane did not significa...
KEY FINDING: Isoflurane anesthesia (1.2%) did not significantly alter LFP amplitude (p = 0.53) in the spinal cord of decerebrated rats.
International Journal of Surgery Case Reports, 2019 • January 9, 2019
This case report describes a previously undocumented complication of brachial plexus paralysis following thoracoscopic esophagectomy in the prone position. The injury was likely caused by the patient'...
KEY FINDING: Brachial plexus injury can occur during thoracoscopic esophagectomy in the prone position, likely due to excessive abduction and external rotation of the arm.
BMC Neuroscience, 2019 • July 23, 2019
This study investigated whether post-surgical inhibition of PI3K could alleviate postoperative pain (POP) and the underlying mechanisms in mice subjected to plantar incision. The results demonstrated ...
KEY FINDING: Post-surgical inhibition of PI3K significantly reduced mechanical allodynia, thermal hyperalgesia, and cumulative pain scores in male mice after plantar incision.
J Anesth, 2012 • June 19, 2012
This case series study prospectively examined whether the effect of spinal anesthesia (SA) could be checked in patients with spinal cord injury (SCI) based on the disappearance of lower extremity refle...
KEY FINDING: The effect of SA in 39 patients (97.5 %) was confirmed by demonstrating the absence of both the Babinski sign and patellar tendon reflex and loss of spasticity after SA.
Clinics, 2012 • November 1, 2012
This study highlights the anesthetic and perioperative management of five patients with high cervical spinal cord injury who underwent laparoscopic insertion of a diaphragmatic pacemaker. The procedur...
KEY FINDING: The diaphragmatic pacemaker placement was successful in all five patients who participated in the study.
Annals of Rehabilitation Medicine, 2013 • June 1, 2013
The case report describes a 44-year-old woman who developed flaccid paralysis of the left leg following thoracic epidural catheterization after abdominal surgery. Neurological assessments, MRI, and el...
KEY FINDING: MRI showed a well-defined intramedullary linear high signal intensity lesion on T2-weighted image and low-signal intensity on T1-weighted image in the spinal cord between T9 and L1 vertebral level.
Saudi Journal of Anaesthesia, 2013 • October 1, 2013
This study evaluates the efficacy of the interadductor approach for obturator neurolysis in 20 spastic patients using 6% phenol, guided by a peripheral nerve stimulator. The interadductor approach was...
KEY FINDING: The interadductor approach for obturator nerve block achieved a 100% success rate with a mean time of 4.9 minutes to accurately locate the nerve.