Browse the latest research summaries in the field of anesthesiology for spinal cord injury patients and caregivers.
Showing 41-46 of 46 results
Frontiers in Cellular Neuroscience, 2021 • December 15, 2021
This study confirms that a clinical concentration of general anesthetic sevoflurane increased the expression of inflammatory factors in microglia and activated the caspase-3 by upregulating ATPIF1 expr...
KEY FINDING: Sevoflurane upregulates the expression of ATPIF1 to induce inflammation and caspase-3 activation.
Frontiers in Cellular Neuroscience, 2022 • May 19, 2022
This corrigendum addresses errors found in Figure 5 of the original article concerning ATPIF1's role in sevoflurane-induced microglial inflammatory responses. The errors involved incorrect labeling in ...
KEY FINDING: Correction of identification errors of notes (E–J) in the legend for Figure 5.
Neural Regeneration Research, 2015 • November 1, 2015
The study aimed to determine if intrathecal propofol administration could protect the spinal cord from ischemia-induced damage. Rats pre-treated with intrathecal propofol (100 µg and 300 µg) showed im...
KEY FINDING: Pre-treatment with intrathecal propofol significantly decreased hind limb motor dysfunction in rats with ischemic spinal cord injury 24 hours after ischemia/reperfusion.
Neural Regeneration Research, 2017 • January 1, 2017
This study investigates the neuroprotective effects of propofol on the blood-spinal cord barrier (BSCB) after ischemia/reperfusion injury (IRI) in rabbits. Spinal cord IRI was induced by infrarenal ao...
KEY FINDING: Propofol decreased histological damage to the spinal cord, indicating a protective effect on the tissue structure after ischemia/reperfusion injury.
Neural Regeneration Research, 2017 • March 1, 2017
Anesthesiologists must understand the pathophysiology of acute cervical spinal cord injuries (CSCI) to prevent secondary injury and improve patient outcomes. This includes careful preoperative assessm...
KEY FINDING: Maintaining mean arterial blood pressure (MAP) at 85 to 90 mmHg in the first week following injury can improve spinal perfusion.
Regeneration, 2017 • January 1, 2017
This study investigated the applicability of propofol as an immersion anesthetic in axolotls, focusing on its effects on cardiovascular function, action potential propagation in the spinal cord, and g...
KEY FINDING: Propofol has significantly less cardiovascular effect than benzocaine and MS-222 when used as an anesthetic in axolotls.