Browse the latest research summaries in the field of anesthesiology for spinal cord injury patients and caregivers.
Showing 1-10 of 46 results
Annals of Medicine, 2024 • April 16, 2024
Complex regional pain syndrome (CRPS) is a debilitating and complex condition that places a significant physical, psychological and emotional burden upon afflicted patients necessitating multi-modal a...
KEY FINDING: CRPS can be classified into two main categories: type 1 and type 2, with type 2 resulting from nerve damage.
Cureus, 2025 • February 22, 2025
This retrospective study examined the impact of volatile anesthetics (desflurane vs. sevoflurane) on functional outcomes in cervical SCI patients undergoing upper extremity nerve transfer procedures. ...
KEY FINDING: The desflurane group had greater median motor strength than the sevoflurane group towards the final follow-up when the desflurane group had median motor strength of 3 [interquartile range (IQR): 1-4] and sevoflurane group had a median motor strength of 1 (IQR: 0-2.25); p=0.014.
Neurochemical Research, 2025 • March 17, 2025
The study examined the protective effect of DEX on remifentanil-induced hyperalgesia in rats. Remifentanil, while effective for pain relief, can paradoxically increase pain sensitivity. The findings i...
KEY FINDING: DEX administration reduced mechanical allodynia and thermal hyperalgesia in rats experiencing remifentanil-induced hyperalgesia (RIH).
J Vet Intern Med, 2022 • September 1, 2022
This study compared the effects of fentanyl versus a ketamine-dexmedetomidine combination on recovery after spinal surgery in dogs with thoracolumbar intervertebral disc herniation. The primary outcom...
KEY FINDING: There was no significant difference in the time to recovery of ambulation between dogs treated with fentanyl and those treated with ketamine-dexmedetomidine.
BMC Anesthesiology, 2022 • August 12, 2022
This study investigated the haemodynamic profiles of patients with acute spinal cord injury (SCI) using the PiCCO™ system, focusing on data unaffected by vasopressor use and other confounding factors....
KEY FINDING: The study found that systemic vascular resistance index (SVRI) was significantly reduced compared to normal ranges in non-SCI patients, regardless of vasopressor use.
BMC Anesthesiology, 2022 • September 1, 2022
This case report describes a rare instance of spinal cord infarction (SCI) secondary to pulmonary embolism (PE)-induced cardiac arrest (CA). The patient, a 72-year-old woman, developed paraplegia afte...
KEY FINDING: A 72-year-old woman developed paraplegia after resuscitation from pulmonary embolism-induced cardiac arrest.
J South Med Univ, 2022 • August 1, 2022
This study aimed to determine the mechanism of xenon post-conditioning in treating spinal cord ischemia-reperfusion injury (SCIRI) in rats, focusing on the mTOR pathway and endoplasmic reticulum stres...
KEY FINDING: Xenon post-conditioning significantly improved hind limb motor function following SCIRI, as indicated by increased BBB and Tarlov scores.
Anaesthesia, 2022 • October 1, 2022
This review addresses airway management in patients with suspected or confirmed traumatic spinal cord injury, aiming to guide best clinical practice. MILS is shown to potentially worsen laryngeal view...
KEY FINDING: Manual in-line stabilization (MILS) may worsen the laryngeal view during direct laryngoscopy, increasing the risk of failed intubation.
Medicina, 2022 • September 7, 2022
This case report describes a spinal cord injury following cervical interlaminar epidural steroid injection (CIESI) in a 35-year-old woman, highlighting potential risks and complications associated wit...
KEY FINDING: Fluoroscopy does not guarantee the prevention of spinal cord penetration during CIESI procedures.
Journal of Neurotrauma, 2023 • December 1, 2023
The study demonstrates that general anesthetics, when administered before a painful stimulus after spinal cord injury (SCI), can protect against secondary injury by blocking pain-induced inflammation ...
KEY FINDING: General anesthetics (pentobarbital and isoflurane) administered before noxious stimulation blocked nociception-induced hemorrhage and eliminated disruption in locomotor recovery.