Browse the latest research summaries in the field of alternative medicine for spinal cord injury patients and caregivers.
Showing 11-20 of 188 results
Journal of Inflammation Research, 2025 • February 17, 2025
This study investigated the synergistic effects of combining Shinbaro and celecoxib in a mouse model of CFA-induced inflammatory pain. The results demonstrated that the combination therapy effectively...
KEY FINDING: The combination of Shinbaro and celecoxib synergistically reduced mechanical hyperalgesia and paw edema in mice with CFA-induced inflammatory pain.
Journal of Pain Research, 2025 • March 7, 2025
This study investigates the therapeutic effects of electroacupuncture (EA) on neuropathic pain (NP) in a rat model. The research focuses on the role of NLRP3 inflammasome-mediated pyroptosis in microg...
KEY FINDING: EA treatment significantly alleviated pain hypersensitivity by increasing the MWT and PWL in CCI rats.
Cureus, 2025 • March 20, 2025
This case series investigates the rapid reversal of forearm supinator rigidity using topical isomerized potassium linoleate (KCLA) in five patients diagnosed with vertigo of central origin. The study ...
KEY FINDING: Topical application of isomerized potassium linoleate (KCLA) rapidly reduced tenderness in the forearm supinator muscle within 2-4 minutes.
African Health Sciences, 2024 • December 1, 2024
This review summarizes the protective effects of Ginsenoside Rd (GSRd) in central nervous system diseases, highlighting its ability to cross the blood-brain barrier and its potential therapeutic appli...
KEY FINDING: Ginsenoside Rd (GSRd) has shown protective effects in neurological diseases such as ischemic stroke, spinal cord injury, Alzheimer's disease and Parkinson's disease.
The Journal of Spinal Cord Medicine, 2023 • January 1, 2023
This study aimed to investigate the effect of Buyang Huanwu decoction (BYHWD) on neural recovery after spinal cord injury (SCI) in rats, focusing on the mTOR signaling pathway and autophagy. The resul...
KEY FINDING: BYHWD improved motor function in SCI rats. Specifically, low, medium, and high doses of BYHWD showed improvements, with the high dose showing the most significant effect.
Frontiers in Neuroscience, 2022 • August 23, 2022
This review examines the neuroprotective effects of ginsenosides on spinal cord injury (SCI), focusing on their mechanisms of action. It highlights ginsenosides' potential as an adjuvant therapy in tr...
KEY FINDING: Ginsenosides exhibit anti-inflammatory properties by modulating the activity of microglia and astrocytes, reducing the expression of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, and influencing T lymphocyte recruitment and infiltration into the spinal cord.
Frontiers in Pharmacology, 2022 • August 24, 2022
Puerarin demonstrates a protective effect against ischemia-reperfusion injury (IRI) in various organs, including the heart, brain, spinal cord, lung, and intestine. The protective mechanisms of puerar...
KEY FINDING: Puerarin reduces myocardial apoptosis by reducing lactic acid production, inhibiting inflammatory response, inhibiting oxidative stress, opening the potassium channel and activating protein kinase C (PKC), promoting myocardial angiogenesis and inhibiting autophagy.
Frontiers in Pharmacology, 2022 • September 5, 2022
This review summarizes the neuroprotective effects of TMP on various CNS diseases, including ICVD, SCI, PD, AD, CI, MI, and depression. The protective effects of TMP against these CNS diseases are bas...
KEY FINDING: TMP exhibits neuroprotective effects against ischemic cerebrovascular diseases by inhibiting calcium overload, glutamate excitotoxicity, oxidative stress, inflammation, and apoptosis, while also protecting the blood-brain barrier and enhancing synaptic plasticity.
Frontiers in Pharmacology, 2022 • October 5, 2022
Spinal cord injury (SCI) is a devastating condition with limited effective treatments. Oxidative stress (OS) significantly contributes to secondary injury mechanisms following SCI. Traditional Chinese...
KEY FINDING: Oxidative stress plays a vital role in secondary injury after SCI, leading to damage of biological macromolecules, ion imbalances, and mitochondrial dysfunctions.
Frontiers in Pharmacology, 2022 • October 19, 2022
Neurological diseases pose a significant burden, and their complex pathogenesis necessitates multi-targeted treatments. Traditional Chinese medicine, particularly TWHF extracts like triptolide and cel...
KEY FINDING: Triptolide and celastrol exhibit therapeutic effects in Alzheimer's disease by inhibiting Aβ deposition, reducing neuroinflammation, decreasing ROS levels, attenuating apoptosis, enhancing autophagy, and exerting neurotrophic effects.