Browse the latest research summaries in the field of alternative medicine for spinal cord injury patients and caregivers.
Showing 181-188 of 188 results
Neural Regen Res, 2018 • December 1, 2018
This study investigates the neuroprotective effect of Huangqin flavonoid extraction on spinal cord injury (SCI) in rats. The researchers administered the extraction to rats with SCI and assessed motor...
KEY FINDING: Huangqin flavonoid extraction markedly reduced spinal cord hematoma, inflammatory cell infiltration and cavities and scars, and increased the Basso, Beattie, and Bresnahan locomotor scale scores; these effects were identical to those of methylprednisolone.
Neural Regeneration Research, 2019 • April 1, 2019
This study evaluated the therapeutic potential of Qian-Zheng-San (QZS) on sciatic nerve crush injury in rats. Results indicated that QZS promoted nerve regeneration, improved nerve function, and enhan...
KEY FINDING: Qian-Zheng-San (QZS) treatment resulted in a higher sciatic nerve function index (SFI) in rats at 2 and 4 weeks post-surgery compared to the control group, indicating improved motor function.
Evidence-Based Complementary and Alternative Medicine, 2019 • March 14, 2019
This study investigates the effects of Alpinia oxyphylla (AO-1) on experimental autoimmune encephalomyelitis (EAE) in mice, a model for multiple sclerosis (MS). The results demonstrate that AO-1 ameli...
KEY FINDING: AO-1 significantly reduced EAE symptoms in mice, as evidenced by decreased EAE scores and attenuated neurological disorders.
Frontiers in Pharmacology, 2019 • July 17, 2019
This study investigates the mechanism by which Bu Shen Yi Sui formula (BSYS), a traditional Chinese medicine, promotes axonal regeneration in multiple sclerosis (MS) and its animal model, experimental...
KEY FINDING: BSYS-containing serum increased cell viability and levels of GAP-43, p-CREB, BDNF, TrkB, and p-PI3K in damaged SH-SY5Y cells.
Neural Regen Res, 2020 • October 18, 2019
This study investigates the protective effects of rhodioloside (Rho) and bone marrow mesenchymal stem cells (BMSCs) infected with HIF-1-expressing adenovirus on acute spinal cord injury (SCI) in a rat...
KEY FINDING: The group treated with both rhodioloside and HIF-1-expressing MSCs showed the highest combined behavioral score, indicating better motor function recovery.
Neuropsychiatric Disease and Treatment, 2019 • November 21, 2019
This study investigates the mechanism of EA treatment on SCI at the molecular level, focusing on the Nogo/NgR and Rho/ROCK signaling pathways. EA may have an inhibitory effect on the Nogo/NgR and Rho/...
KEY FINDING: EA treatment significantly reduced mRNA and protein expression of Nogo-A, NgR, LINGO-1, RhoA and ROCK II in spinal cord tissues of SCI rats.
Neural Plasticity, 2020 • September 25, 2020
This review discusses the potential of combining acupuncture with mesenchymal stem cell (MSC) transplantation as a novel strategy for treating spinal cord injury (SCI). Acupuncture alone has shown eff...
KEY FINDING: Acupuncture improves sensory and motor function in SCI patients by improving activity of daily living (ADL). Pooled analyses in a meta-analysis showed that acupuncture had a beneficial effect on neurological recovery (relative risk: 1.28, 95% confidence interval (CI): 1.12-1.50), motor function (weighted mean difference: 6.86, 95% CI: 0.41-13.31), and functional recovery (standardized mean difference: 0.88, 95% CI: 0.56-1.21).
iScience, 2021 • February 19, 2021
This study provides in vivo evidence showing that repeated EA treatment modulates the cortical circuit to relieve neuropathic pain. The activation of CB1R by EA leads to presynaptic inhibition at GABA...
KEY FINDING: EA treatment reduces both mechanical and thermal hypersensitivity in mice with neuropathic pain, indicating its analgesic effects.