Browse the latest research summaries in the field of aging for spinal cord injury patients and caregivers.
Showing 51-60 of 150 results
GeroScience, 2021 • October 13, 2021
This correction addresses an error in the original publication concerning Figure 1 and its legend. The corrected figure presents data from experiments on aged and young rats, focusing on neuromuscular...
KEY FINDING: Aged rats show significant deficits in neuromuscular junction transmission.
Journal of Frailty, Sarcopenia and Falls, 2021 • December 1, 2021
Osteosarcopenia has been proposed as a syndrome in a subset of frail individuals at higher risk of falls, fractures and institutionalization. A new holistic concept called Osteosarcopenia School will ...
KEY FINDING: Osteosarcopenia and osteosarcopenia with a severe sarcopenia component may occur in both osteoporotic and osteopenic individuals, increasing symmetrically fracture risk.
Journal of Neurotrauma, 2022 • May 1, 2022
This multi-center study aimed to identify predictors of neurological improvement in elderly patients with CSCI without major bone injury. In AIS A–C cases, body mass index (OR: 1.112), magnetic resona...
KEY FINDING: In AIS A–C cases, body mass index (BMI), MRI signal change, AIS grade on admission, dementia/delirium comorbidity, and post-injury pneumonia were identified as independent prognostic factors for walking recovery.
Journals of Gerontology: Biological Sciences, 2022 • October 1, 2022
This study characterized the effects of laparotomy on postoperative physical function and skeletal muscle gene expression in male C57BL/6N mice across life span. The study found that laparotomy-induce...
KEY FINDING: Laparotomy induced an age-associated postoperative decline in forelimb grip strength, with the greatest decline in the oldest mice.
European Journal of Physical and Rehabilitation Medicine, 2022 • June 1, 2022
This study explored falls among SCI patients and the ability of three clinical measures, including the HG test, SCIM III and ULL-SPUT, to discriminate between individuals with SCI with and without a h...
KEY FINDING: The ULL-SPUT data of faller participants were significantly higher than those of non-fallers (P<0.05).
Frontiers in Neurology, 2022 • March 22, 2022
This study assessed the reliability and validity of the Composite Activity-Related Fall Risk Scale (CARFS) in older adults, persons with stroke, and persons with spinal cord injury. The CARFS demonstr...
KEY FINDING: The CARFS demonstrated excellent test-retest reliability in assessing fear of falling, physical behavior, and composite activity-related fall risk.
Top Spinal Cord Inj Rehabil, 2022 • July 1, 2022
This systematic review examined the relationship between lower limb function and fall prevalence in ambulatory individuals with spinal cord injury (SCI). The review included 13 studies, revealing inco...
KEY FINDING: The qualitative analysis provided little evidence to support the relationship between lower limb function recorded by clinical measures and fall prevalence.
PLoS ONE, 2022 • June 7, 2022
This study explored the impact of falls and fall risk on individuals with subacute SCI/D as they transitioned from inpatient rehabilitation to community living. Four main themes were revealed: risk fa...
KEY FINDING: Participants identified their own risk factors for falls through personal experiences, often learning through trial and error.
Oxidative Medicine and Cellular Longevity, 2022 • July 8, 2022
This study investigates the mechanisms by which MANF facilitates the clearance of α-synuclein (SNCA), a key protein implicated in Parkinson's disease (PD). The research demonstrates that MANF activate...
KEY FINDING: MANF reduces Parkinsonian behavior and α-synuclein accumulation in a rotenone-induced PD mouse model.
BMC Musculoskeletal Disorders, 2022 • August 9, 2022
This multicenter study analyzed data from 313 elderly patients who underwent spinal fusion surgery for cervical fractures to determine 1-year mortality and changes in walking capacity. The study found...
KEY FINDING: The 1-year mortality rate after spinal fusion surgery for cervical fractures in elderly patients was 8%.